Name : HOXD9 Antibody, ALEXA FLUOR 594
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN6135709634
| Long name | ALEXA FLUOR 594 Conjugated, HOXD9 Polyclonal Antibody |
| Also known as | Anti-HOXD9 PAb ALEXA FLUOR 594 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 594, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | HOXD9 |
| Specificity | This is a highly specific antibody against HOXD9 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human HOXD9 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Activation of HoxD9 depends on the structure of the target regulatory element, Furthermore, HoxD9 may be a multifunctional transcriptional regulator, HoxD9 transcripts are also detected in the synovial tissue of arthritic mice, In vivo, Specifically, The HoxD9 protein is expressed in the early stages of mouse joint development, The human HoxD9 protein is also differentially expressed in the human cervical cancer cell line HeLa, and results in differential cofactor interaction, as it contains different activation domains, but is not expressed in the normal cervix and may thus play a role in tumorigenesis, but not in osteoarthritis patients, but not in that of normal mice, primarily in the articular cartilage, suggesting that HoxD9 may have a role in the pathology of arthritis, the HoxD9 protein interacts with the autoregulatory and cross-regulatory enhancers of the murine HoxB1 and human HoxD9 genes, the HoxD9 protein interacts with the human control region (HCR) of the HoxD9 gene, the HoxD9 protein is highly expressed in the synoviocytes of patients with rheumatoid arthritis (RA), thus inducing transcription of the HoxD9 promoter, The Hox proteins play a role in patterns of embryonic development and cellular differentiation by regulating downstream target genes |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 590nm/617nm |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | 594, ALEXA FLUOR®, Alexa Fluor |
| Conjugated | Alexa conjugate 1 |
| Gene target | HOXD9 |
| Short name | HOXD9 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 594 |
| Alternative name | ALEXA FLUOR 594, HOXD9 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 5140 |
| Gene | HOXD9 |
| Long gene name | homeobox D9 |
| Synonyms gene | HOX4C HOX4 |
| Synonyms gene name | homeo box D9 |
| Locus | 2q31, 1 |
| Discovery year | 1990-06-15 |
| Entrez gene record | 3235 |
| Pubmed identfication | 1973146 1358459 |
| Classification | HOXL subclass homeoboxes |
| Havana BLAST/BLAT | OTTHUMG00000132516 |