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HP1(Tyr43) Antibody

HP1(Tyr43) Antibody size: 0.1ml 281

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 281
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameHP1(Tyr43) Primary Polyclonal Antibody
Also known asHP1(Tyr43) PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenHP1 Tyr43
SpecificityThis is a highly specific antibody against HP1 Tyr43
Modification(s)Phosphorylation
Modification site(s)Tyr43
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from Drosophila Melanogaster HP1 around the phosphorylation site of Tyr43
Gene ID number34119
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivityOther Species
Cross reactive species detailsFruit Fly
Background of the target antigen Both domains of HP1 are required for binding to native chromatin in vivo, HP1 alpha may interact with lamin B receptor (LBR), HP1 proteins are relatively small proteins (~25 kDa) with a conserved amino-terminal chromo domain and a structurally related carboxy-terminal motif, It recognizes and binds histone H3 tails methylated at Lys-9, This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane, but they contribute differentially to binding in euchromatin and heterochromatin, leading to epigenetic repression, the chromo shadow domain, HP1 alpha is a component of heterochromatin
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names CG8409, HP1, Non-histone chromosomal protein C1A9 antigen, Heterochromatin protein 1
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetHP1(Tyr43)
Short nameHP1(Tyr43) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameHP1(Tyr43) (Antibody to)
Alternative techniqueantibodies
Identity 1555
Gene CBX5
Long gene name chromobox 5
Synonyms gene name Drosophila) chromobox homolog 5 , chromobox homolog 5 (Drosophila HP1 alpha) chromobox homolog 5 (HP1 alpha homolog
Synonyms HP1Hs-alpha HP1 HP1-ALPHA
Synonyms name HP1 alpha homolog (Drosophila)
Locus 12q13, 13
Discovery year 1999-10-12
GenBank acession U26311
Entrez gene record 23468
Pubmed identfication 8663349
RefSeq identity NM_012117
Classification Chromobox family
Havana BLAST/BLAT OTTHUMG00000169700

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