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HP1(Tyr43) Antibody, ALEXA FLUOR 488

HP1(Tyr43) Antibody, ALEXA FLUOR 488 size: 100ul 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 350
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 488 Conjugated, HP1(Tyr43) Polyclonal Antibody
Also known asAnti-HP1 Tyr43 PAb ALEXA FLUOR 488
CategoryConjugated Primary Antibodies
Conjugated with 488, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenHP1 Tyr43
SpecificityThis is a highly specific antibody against HP1 Tyr43
ModificationPhosphorylation
Modification SiteTyr43
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from Drosophila Melanogaster HP1 around the phosphorylation site of Tyr43
Gene ID Number34119
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
CrossreactivityOther Species
Cross-reactive species detailsFruit Fly
Background of the antigen Both domains of HP1 are required for binding to native chromatin in vivo, HP1 alpha may interact with lamin B receptor (LBR), HP1 proteins are relatively small proteins (~25 kDa) with a conserved amino-terminal chromo domain and a structurally related carboxy-terminal motif, It recognizes and binds histone H3 tails methylated at Lys-9, This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane, but they contribute differentially to binding in euchromatin and heterochromatin, leading to epigenetic repression, the chromo shadow domain, HP1 alpha is a component of heterochromatin
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission499nm/519nm
Synonyms HP1Hs-alpha HP1 HP1-ALPHA
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the HP1(Tyr43) Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetHP1(Tyr43)
Short nameHP1(Tyr43) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 488
Alternative name ALEXA FLUOR 488, HP1(Tyr43) (Antibody to)
Alternative techniqueantibodies
Identity 1555
Gene CBX5
Long gene name chromobox 5
Synonyms gene name Drosophila) chromobox homolog 5 , chromobox homolog 5 (Drosophila HP1 alpha) chromobox homolog 5 (HP1 alpha homolog
Synonyms name HP1 alpha homolog (Drosophila)
Locus 12q13, 13
Discovery year 1999-10-12
GenBank acession U26311
Entrez gene record 23468
Pubmed identfication 8663349
RefSeq identity NM_012117
Classification Chromobox family
Havana BLAST/BLAT OTTHUMG00000169700

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