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HP1(Tyr43) Antibody, Cy5 Conjugated

HP1(Tyr43) Antibody, Cy5 Conjugated size: 0.1ml 368

Price 368
Size 0.1ml
Long name Cy5 Conjugated, HP1(Tyr43) Polyclonal Antibody
CategoryConjugated Primary Antibodies
Conjugation5, Cy5
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenHP1 Tyr43
SpecificityThis is a highly specific antibody against HP1 Tyr43
ModificationPhosphorylation
Modification siteTyr43
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from Drosophila Melanogaster HP1 around the phosphorylation site of Tyr43
Gene ID number34119
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
CrossreactivityOther Species
Crossreactive species detailsFruit Fly
Antigen background Both domains of HP1 are required for binding to native chromatin in vivo, HP1 alpha may interact with lamin B receptor (LBR), HP1 proteins are relatively small proteins (~25 kDa) with a conserved amino-terminal chromo domain and a structurally related carboxy-terminal motif, It recognizes and binds histone H3 tails methylated at Lys-9, This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane, but they contribute differentially to binding in euchromatin and heterochromatin, leading to epigenetic repression, the chromo shadow domain, HP1 alpha is a component of heterochromatin
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission625, 650nm/670nm
Synonyms HP1Hs-alpha HP1 HP1-ALPHA
Properties Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetHP1(Tyr43) Conjugated
Short name Conjugated, HP1(Tyr43) Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy5
Alternative name cyanine 5 coupled, HP1(Tyr43) (Antibody to)
Alternative techniqueantibodies
Identity 1555
Gene CBX5
Long gene name chromobox 5
Synonyms gene name Drosophila) chromobox homolog 5 , chromobox homolog 5 (Drosophila HP1 alpha) chromobox homolog 5 (HP1 alpha homolog
Synonyms name HP1 alpha homolog (Drosophila)
Locus 12q13, 13
Discovery year 1999-10-12
GenBank acession U26311
Entrez gene record 23468
Pubmed identfication 8663349
RefSeq identity NM_012117
Classification Chromobox family
Havana BLAST/BLAT OTTHUMG00000169700

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