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HP1(Tyr43) Antibody, FITC Conjugated

HP1(Tyr43) Antibody, FITC Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, HP1(Tyr43) Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenHP1 Tyr43
SpecificityThis is a highly specific antibody against HP1 Tyr43
ModificationPhosphorylation
Modification siteTyr43
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from Drosophila Melanogaster HP1 around the phosphorylation site of Tyr43
Gene ID number34119
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
CrossreactivityOther Species
Crossreactive species detailsFruit Fly
Antigen background Both domains of HP1 are required for binding to native chromatin in vivo, HP1 alpha may interact with lamin B receptor (LBR), HP1 proteins are relatively small proteins (~25 kDa) with a conserved amino-terminal chromo domain and a structurally related carboxy-terminal motif, It recognizes and binds histone H3 tails methylated at Lys-9, This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane, but they contribute differentially to binding in euchromatin and heterochromatin, leading to epigenetic repression, the chromo shadow domain, HP1 alpha is a component of heterochromatin
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms HP1Hs-alpha HP1 HP1-ALPHA
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetHP1(Tyr43) Conjugated
Short name FITC Conjugated, HP1(Tyr43) Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, HP1(Tyr43) (Antibody to)
Alternative techniqueantibodies
Identity 1555
Gene CBX5
Long gene name chromobox 5
Synonyms gene name Drosophila) chromobox homolog 5 , chromobox homolog 5 (Drosophila HP1 alpha) chromobox homolog 5 (HP1 alpha homolog
Synonyms name HP1 alpha homolog (Drosophila)
Locus 12q13, 13
Discovery year 1999-10-12
GenBank acession U26311
Entrez gene record 23468
Pubmed identfication 8663349
RefSeq identity NM_012117
Classification Chromobox family
Havana BLAST/BLAT OTTHUMG00000169700

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