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HPV33 E6 Antibody, Biotin Conjugated

HPV33 E6 Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, HPV33 E6 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenHPV33 E6
Specificity HPV58, This antibody will detect E6 in HPV33, and Alphapapillomavirus 9, This is a highly specific antibody against HPV33 E6
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range90-140/149
Subcellular locationNucleus
SourceKLH conjugated synthetic peptide derived from human HPV33 E6 protein
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
CrossreactivityVirus
Crossreactive species details Alphapapillomavirus 9, HPV58, HPV33
Antigen background 31 and 33, Approximately 90% of cervical cancers contain HPV DNA of the high risk types, Binds double-stranded DNA, HPV16 and HPV18 are the most common of the high risk group while HPV6 and HPV11 are among the low risk types, However, Human papillomaviruses (HPV) are small DNA viruses which infect epithelia of the skin and mucosa, Mutational analysis have shown that the E6 and E7 genes of the high risk HPVs are necessary and sufficient for HPV transforming function, Over 90 types have been identified and they mostly cause a variety of benign lesions such as warts and verrucae, The E6 protein is a transcriptional transactivator, The high risk HPV E7 proteins bind to pRB with a higher affinity than do the low risk HPV proteins, The specific interactions of the E6 and E7 proteins with p53 and pRB, This protein may be involved in the oncogenic potential of this virus (cervical neoplasia-associated virus), and only the high risk HPV E6 proteins form detectable complexes with p53 in vitro, correlate with HPV high and low risk classifications, have been confirmed as agents which cause cervical cancer, notably types 16 and 18, respectively, some subtypes, Human papilloma viruses (HPVs) can be classified as either high risk or low risk according to their association with cancer
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms HPV33 E6 protein, HPV33-E6 protein, Human Papilloma Virus, Human papillomavirus type 33, Human papillomavirus type 33, Protein 33, VE6_HPV33, E6 protein [Human papillomavirus type 33]
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetHPV33 E6 Conjugated
Short name Conjugated, HPV33 E6 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, HPV33 E6 (Antibody to)
Alternative techniqueantibodies

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