Name : HPV33 E6 Antibody, Cy5.5 Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :350
SKU : GEN8045315443
| Long name | Cy5, 5 Conjugated, HPV33 E6 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Cy5, 5, 5, Cy5 |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | HPV33 E6 |
| Specificity | HPV58, This antibody will detect E6 in HPV33, and Alphapapillomavirus 9, This is a highly specific antibody against HPV33 E6 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen_range | 90-140/149 |
| Subcellular location | Nucleus |
| Source | KLH conjugated synthetic peptide derived from human HPV33 E6 protein |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Virus |
| Crossreactive species details | Alphapapillomavirus 9, HPV58, HPV33 |
| Antigen background | 31 and 33, Approximately 90% of cervical cancers contain HPV DNA of the high risk types, Binds double-stranded DNA, HPV16 and HPV18 are the most common of the high risk group while HPV6 and HPV11 are among the low risk types, However, Human papillomaviruses (HPV) are small DNA viruses which infect epithelia of the skin and mucosa, Mutational analysis have shown that the E6 and E7 genes of the high risk HPVs are necessary and sufficient for HPV transforming function, Over 90 types have been identified and they mostly cause a variety of benign lesions such as warts and verrucae, The E6 protein is a transcriptional transactivator, The high risk HPV E7 proteins bind to pRB with a higher affinity than do the low risk HPV proteins, The specific interactions of the E6 and E7 proteins with p53 and pRB, This protein may be involved in the oncogenic potential of this virus (cervical neoplasia-associated virus), and only the high risk HPV E6 proteins form detectable complexes with p53 in vitro, correlate with HPV high and low risk classifications, have been confirmed as agents which cause cervical cancer, notably types 16 and 18, respectively, some subtypes, Human papilloma viruses (HPVs) can be classified as either high risk or low risk according to their association with cancer |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 675nm/694nm |
| Synonyms | HPV33 E6 protein, HPV33-E6 protein, Human Papilloma Virus, Human papillomavirus type 33, Human papillomavirus type 33, Protein 33, VE6_HPV33, E6 protein [Human papillomavirus type 33] |
| Properties | Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated | These antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths |
| Gene target | HPV33 E6 Conjugated |
| Short name | Conjugated, HPV33 E6 Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | 5, Cy5 |
| Alternative name | cyanine 5, 5 coupled, HPV33 E6 (Antibody to) |
| Alternative technique | antibodies |