Name : HPV33 E7 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN2032481830
| Long name | HPV33 E7 Primary Polyclonal Antibody |
| Also known as | HPV33 E7 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | HPV33 E7 |
| Specificity | This antibody will also detect E7 in HPV58, but with slightly less affinity, due to a one amino acid change in the immunogen sequence range, This is a highly specific antibody against HPV33 E7 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 30-80/97 |
| Subcellular location | Nucleus |
| Source | KLH conjugated synthetic peptide derived from HPV33 E7 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Virus |
| Cross reactive species details | HPV33 |
| Background of the target antigen | Disrupts the function of host retinoblastoma protein RB1/pRb, Inactivation of the ability of RB1 to arrest the cell cycle is critical for cellular transformation, Induces the disassembly of the E2F1 transcription factors from RB1, Interferes with histone deacetylation mediated by HDAC1 and HDAC2, Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication, leading to activation of transcription (By similarity), uncontrolled cellular growth and proliferation induced by viral infection, which is a key regulator of the cell cycle, with subsequent transcriptional activation of E2F1-regulated S-phase genes, E7 protein has both transforming and trans-activating activities |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | Human Papilloma Virus, Human papillomavirus type 33, Human papillomavirus type 33, Protein 33, early protein E7 [Human papillomavirus type 33], E7 protein [Human papillomavirus type 33] |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | HPV33 E7 |
| Short name | HPV33 E7 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | HPV33 E7 (Antibody to) |
| Alternative technique | antibodies |