| Long name | ALEXA FLUOR 555 Conjugated, HRAS+KRAS Polyclonal Antibody |
| Also known as | Anti-HRAS+KRAS PAb ALEXA FLUOR 555 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 555, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | HRAS+KRAS |
| Specificity | This is a highly specific antibody against HRAS+KRAS |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human HRAS+KRAS |
| Gene ID Number | 3265 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | HRAS, The RAS proteins are GDP/GTP-binding proteins that act as intracellular signal transducers, The most well-studied members of the RAS (derived from 'RAt Sarcoma' virus) gene family include KRAS, These genes encode immunologically related proteins with a molecular mass of 21 kD and are homologs of rodent sarcoma virus genes that have transforming abilities, While these wildtype cellular proteins in humans play a vital role in normal tissue signaling, and NRAS, and senescence, differentiation, including proliferation, mutated genes are potent oncogenes that play a role in many human cancers, The KRAS gene encodes the human cellular homolog of a transforming gene isolated from the Kirsten rat sarcoma virus |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 553nm/568nm |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | ALEXA FLUOR 555, Alexa Fluor |
| Gene target | HRAS+KRAS |
| Short name | HRAS+KRAS Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 555 |
| Alternative name | ALEXA FLUOR 555, v-Ha-ras Harvey rat sarcoma viral oncogene homolog+v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | C-BAS/HAS and C-H-RAS and C-HA-RAS1 and CTLO and H-RASIDX and HAMSV and HRAS1 and p21ras and RASH1, C-K-RAS and CFC2 and K-RAS2A and K-RAS2B and K-RAS4A and K-RAS4B and KI-RAS and KRAS1 and KRAS2 and NS and NS3 and RASK2, GABAergic and biological process this GO :0032403 and protein complex binding and molecular function this GO :0035022 and positive regulation of Rac protein signal transduction and biological process this GO :0035176 and social behavior and biological process this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0043406 and positive regulation of MAP kinase activity and biological process this GO :0043524 and negative regulation of neuron apoptotic process and biological process this GO :0045087 and innate immune response and biological process this GO :0045121 and membrane raft and cellular component this GO :0045596 and negative regulation of cell differentiation and biological process this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0048169 and regulation of long-term neuronal synaptic plasticity and biological process this GO :0050900 and leukocyte migration and biological process this GO :0051000 and positive regulation of nitric-oxide synthase activity and biological process this GO :0051092 and positive regulation of NF-kappaB transcription factor activity and biological process this GO :0051146 and striated muscle cell differentiation and biological process this GO :0051384 and response to glucocorticoid and biological process this GO :0051385 and response to mineralocorticoid and biological process this GO :0060441 and epithelial tube branching involved in lung morphogenesis and biological process, GABAergic and biological process this GO :0032855 and positive regulation of Rac GTPase activity and biological process this GO :0034259 and negative regulation of Rho GTPase activity and biological process this GO :0035022 and positive regulation of Rac protein signal transduction and biological process this GO :0035176 and social behavior and biological process this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0043231 and intracellular membrane-bounded organelle and cellular component this GO :0043406 and positive regulation of MAP kinase activity and biological process this GO :0043410 and positive regulation of MAPK cascade and biological process this GO :0043524 and negative regulation of neuron apoptotic process and biological process this GO :0045087 and innate immune response and biological process this GO :0045596 and negative regulation of cell differentiation and biological process this GO :0045740 and positive regulation of DNA replication and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046330 and positive regulation of JNK cascade and biological process this GO :0046579 and positive regulation of Ras protein signal transduction and biological process this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0048169 and regulation of long-term neuronal synaptic plasticity and biological process this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0050679 and positive regulation of epithelial cell proliferation and biological process this GO :0050900 and leukocyte migration and biological process this GO :0051146 and striated muscle cell differentiation and biological process this GO :0051291 and protein heterooli this GO merization and biological process this GO :0060441 and epithelial tube branching involved in lung morphogenesis and biological process this GO :0070374 and positive regulation of ERK1 and ERK2 cascade and biological process this GO :0090303 and positive regulation of wound healing and biological process this GO :0090398 and cellular senescence and biological process this GO :0097193 and intrinsic apoptotic signaling pathway and biological process this GO :1900029 and positive regulation of ruffle assembly and biological process this GO :2000251 and positive regulation of actin cytoskeleton reorganization and biological process this GO :2000630 and positive regulation of miRNA metabolic process and biological process, HRAS and IDBG-16878 and ENSG00000174775 and 3265, HRAS and IDBG-645593 and ENSBTAG00000046644 and 100298939, Hras1 and IDBG-212024 and ENSMUSG00000025499 and 15461, KRAS and IDBG-23889 and ENSG00000133703 and 3845, KRAS and IDBG-638783 and ENSBTAG00000009778 and 541140, Kras and IDBG-197719 and ENSMUSG00000030265 and 16653, Plasma membranes, ferrous iron transmembrane transporter activity, nuclei, protein complex binding, this GO :0000139 and this GO lgi membrane and cellular component this GO :0000165 and MAPK cascade and biological process this GO :0000186 and activation of MAPKK activity and biological process this GO :0001934 and positive regulation of protein phosphorylation and biological process this GO :0003924 and GTPase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005525 and GTP binding and molecular function this GO :0005622 and intracellular and cellular component this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005794 and this GO lgi apparatus and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006184 and GTP catabolic process and biological process this GO :0006897 and endocytosis and biological process this GO :0006915 and apoptotic process and biological process this GO :0006935 and chemotaxis and biological process this GO :0007050 and cell cycle arrest and biological process this GO :0007093 and mitotic cell cycle checkpoint and biological process this GO :0007165 and signal transduction and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007173 and epidermal growth factor receptor signaling pathway and biological process this GO :0007264 and small GTPase mediated signal transduction and biological process this GO :0007265 and Ras protein signal transduction and biological process this GO :0007268 and synaptic transmission and biological process this GO :0007411 and axon guidance and biological process this GO :0007569 and cell aging and biological process this GO :0007596 and blood coagulation and biological process this GO :0008022 and protein C-terminus binding and molecular function this GO :0008283 and cell proliferation and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0008286 and insulin receptor signaling pathway and biological process this GO :0008542 and visual learning and biological process this GO :0008543 and fibroblast growth factor receptor signaling pathway and biological process this GO :0009887 and organ morphogenesis and biological process this GO :0010628 and positive regulation of gene expression and biological process this GO :0010629 and negative regulation of gene expression and biological process this GO :0015031 and protein transport and biological process this GO :0015093 and ferrous iron transmembrane transporter activity and molecular function this GO :0015684 and ferrous iron transport and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0030036 and actin cytoskeleton organization and biological process this GO :0030335 and positive regulation of cell migration and biological process this GO :0032228 and regulation of synaptic transmission, this GO :0000165 and MAPK cascade and biological process this GO :0000186 and activation of MAPKK activity and biological process this GO :0001934 and positive regulation of protein phosphorylation and biological process this GO :0003924 and GTPase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005525 and GTP binding and molecular function this GO :0005622 and intracellular and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006184 and GTP catabolic process and biological process this GO :0006886 and intracellular protein transport and biological process this GO :0006913 and nucleocytoplasmic transport and biological process this GO :0007165 and signal transduction and biological process this GO :0007173 and epidermal growth factor receptor signaling pathway and biological process this GO :0007264 and small GTPase mediated signal transduction and biological process this GO :0007265 and Ras protein signal transduction and biological process this GO :0007411 and axon guidance and biological process this GO :0007596 and blood coagulation and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0008286 and insulin receptor signaling pathway and biological process this GO :0008542 and visual learning and biological process this GO :0008543 and fibroblast growth factor receptor signaling pathway and biological process this GO :0010628 and positive regulation of gene expression and biological process this GO :0015031 and protein transport and biological process this GO :0016020 and membrane and cellular component this GO :0019002 and GMP binding and molecular function this GO :0019003 and GDP binding and molecular function this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0030036 and actin cytoskeleton organization and biological process this GO :0030275 and LRR domain binding and molecular function this GO :0032228 and regulation of synaptic transmission, this GO :0003924: GTPase activity, this GO :0003924: GTPase activity, this GO :0003924: GTPase activity and also this GO :0005515: protein binding and also this GO :0005525: GTP binding and also this GO :0008022: protein C-terminus binding and also this GO :0015093: ferrous iron transmembrane transporter activity, this GO :0003924: GTPase activity and also this GO :0005515: protein binding and also this GO :0005525: GTP binding and also this GO :0019002: GMP binding and also this GO :0019003: GDP binding and also this GO :0030275: LRR domain binding and also this GO :0032403: protein complex binding, this GO :0005515: protein binding, this GO :0005515: protein binding, this GO :0005525: GTP binding, this GO :0005525: GTP binding, this GO :0008022: protein C-terminus binding, this GO :0015093: ferrous iron transmembrane transporter activity, this GO :0019002: GMP binding, this GO :0019003: GDP binding, this GO :0030275: LRR domain binding, this GO :0032403: protein complex binding, v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, v-Ha-ras Harvey rat sarcoma viral oncogene homolog |
| Identity | 5173 |
| Gene | HRAS |
| Long gene name | GTPase , HRas proto-oncogene |
| Synonyms gene | HRAS1 |
| Synonyms gene name | v-Ha-ras Harvey rat sarcoma viral oncogene homolog Harvey rat sarcoma viral oncogene homolog |
| Locus | 11p15, 5 |
| Discovery year | 2001-06-22 |
| GenBank acession | AJ437024 |
| Entrez gene record | 3265 |
| RefSeq identity | NM_176795 |
| Classification | RAS type GTPase family |
| Havana BLAST/BLAT | OTTHUMG00000131919 |
| Locus Specific Databases | LRG_506 |
Technique
Supplier
Species
Label
Iso Type
Host
Tissue