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HSC70 Antibody / HSPA8

HSC70 Antibody / HSPA8 size: 0.1mg 406

Supplier NJS POLY
Price 406
Size 0.1mg
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration2ml sterile DI water, 5mg/ml if reconstituted with 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenHSC70 / HSPA8
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications IHC-P, WB
Recommended dilutions1-0, 5-1ug/ml, 5ug/ml, IHC (Paraffin): 0, Western blot: 0
NotesOptimal dilution of the HSC70 antibody should be determined by the researcher
Intented useThis HSC70 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P11142
PurityAntigen affinity
Description And the HSPA8 gene is mapped on 11q24, FORMERLY, HSC71, HSP73, HSP73 also functions as an ATPase in the disassembly of clathrin-coated vesicles during transport of membrane components through the cell, HSPA10, HSPA8 plays an important role in cells by transiently associating with nascent polypeptides to facilitate correct folding, Hsc70 formed a complex with Hsp40 and Hip, In the absence of Il3, LAP1 or LPS-ASSOCIATED PROTEIN 1, Rapid decay involves AU-rich binding protein AUF1, The HSPA8 gene contains 9 exons and spans 5 kb, The deduced HSPA8 protein has 646 amino acids and a predicted molecular mass of 70, and poly (A)-binding protein, and this complex, formed a high-stability complex with Bim mRNA that protected it from ribonucleases, in association with Eif4g and Pabp, is a heat shock protein that in humans is encoded by the HSPA8 gene, translation initiation factor EIF4G, which complexes with heat-shock proteins HSC70 and HSP70, 1, 899 Da, HSPA8 (heat shock 70kDa protein 8) also known as HSC70
ImmunogenAmino acids 520-614 of human HSPA8/HSC70 were used as the immunogen for the HSC70 antibody
Storage Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the HSC70 antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetHSC70 / HSPA8
Short nameHSC70 Antibody / HSPA8
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameHSC70 (Antibody to) / HSPA8
Alternative techniqueantibodies
Identity 5241
Gene HSPA8
Long gene name heat shock protein family A (Hsp70) member 8
Synonyms gene HSPA10
Synonyms gene name heat shock 70kD protein 8 heat shock 70kDa protein 8
Synonyms HSC71 HSC70 HSP73
Locus 11q24, 1
Discovery year 1995-05-08
GenBank acession Y00371
Entrez gene record 3312
Pubmed identfication 8530083 3037489
Classification NineTeen complex Heat shock 70kDa proteins
Havana BLAST/BLAT OTTHUMG00000166030

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