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HSD17B4 Antibody

HSD17B4 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameHSD17B4 Primary Polyclonal Antibody
Also known asHSD17B4 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenHSD17B4
SpecificityThis is a highly specific antibody against HSD17B4
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human HSD17B4 Enoyl-CoA hydratase 2
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen 17Beta-HSD4 inactivates Estradiol through its oxidative activity but it is primarily involved in peroxisomal fatty acid and cholesterol Beta-oxidation, 17Beta-HSD4 is a target protein of chromeceptin and it is essential for the downstream activation of Stat6, 17Beta-HSD4-deficient patients exhibit Zellweger-like syndrome and die within the first year of life, D-bifunctional enzyme or 17-Beta Estradiol dehydrogenase type IV, It belongs to the 17Beta-HSD family of proteins that regulate the availability of steroids within various tissues throughout the body, It has a multi-domain structure: the dehydrogenase domain is fused to a hydratase and a lipid transfer domain, They display neuronal migration defects, facial dysmorphisms, severe hypotonia and convulsions in the neonatal period, 17Beta-HSD4 (17Beta-hydroxysteroid dehydrogenase type 4) is also known as peroxisomal multifunctional enzyme/protein 2 (MFE-2/MFP-2)
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names 12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase, 17 beta HSD 4, 17 beta HSD IV, 17 beta hydroxysteroid dehydrogenase 4, 17-beta-HSD 4, 17-beta-hydroxysteroid dehydrogenase 4, 17beta estradiol dehydrogenase type IV, 3 alpha 7 alpha12 alpha trihydroxy 5 beta cholest 24 enoyl CoA hydratase antibody 3-alpha, 7-alpha, Beta hydroxyacyl dehydrogenase, Beta keto reductase, D 3 hydroxyacyl CoA dehydratase, D bunctional protein, D bunctional protein peroxisomal, D-bunctional protein, DBP, DHB4_HUMAN, EDH17B4, Enoyl-CoA hydratase 2, Hsd17b4, MFE 2, MFE-2, MPF-2, Multunctional protein 2, Peroxisomal multunctional enzyme type 2, Peroxisomal multunctional protein 2, SDR8C1, Short chain dehydrogenase/reductase family 8C member 1, hydroxysteroid 17-beta dehydrogenase 4
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetHSD17B4
Short nameHSD17B4 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameHSD17B4 (Antibody to)
Alternative techniqueantibodies
Identity 5213
Gene HSD17B4
Long gene name hydroxysteroid 17-beta dehydrogenase 4
Synonyms gene name hydroxysteroid (17-beta) dehydrogenase 4
Synonyms MFE-2 DBP SDR8C1
Synonyms name 17beta-estradiol dehydrogenase type IV peroxisomal multifunctional protein 2 17-beta-HSD IV 17-beta-hydroxysteroid dehydrogenase 4 D-bifunctional protein, member 1 , peroxisomal D-3-hydroxyacyl-CoA dehydratase 3-alpha, 12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase beta-keto-reductase beta-hydroxyacyl dehydrogenase short chain dehydrogenase/reductase family 8C, 7-alpha
Locus 5q23, 1
Discovery year 1994-09-14
Entrez gene record 3295
Pubmed identfication 8938456 19027726
RefSeq identity NM_000414
Classification Short chain dehydrogenase/reductase superfamily
Havana BLAST/BLAT OTTHUMG00000128899

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