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HSD17B4 Antibody, Cy7 Conjugated

HSD17B4 Antibody, Cy7 Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Cy7 Conjugated, HSD17B4 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationCy7
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenHSD17B4
SpecificityThis is a highly specific antibody against HSD17B4
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human HSD17B4 Enoyl-CoA hydratase 2
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background 17Beta-HSD4 inactivates Estradiol through its oxidative activity but it is primarily involved in peroxisomal fatty acid and cholesterol Beta-oxidation, 17Beta-HSD4 is a target protein of chromeceptin and it is essential for the downstream activation of Stat6, 17Beta-HSD4-deficient patients exhibit Zellweger-like syndrome and die within the first year of life, D-bifunctional enzyme or 17-Beta Estradiol dehydrogenase type IV, It belongs to the 17Beta-HSD family of proteins that regulate the availability of steroids within various tissues throughout the body, It has a multi-domain structure: the dehydrogenase domain is fused to a hydratase and a lipid transfer domain, They display neuronal migration defects, facial dysmorphisms, severe hypotonia and convulsions in the neonatal period, 17Beta-HSD4 (17Beta-hydroxysteroid dehydrogenase type 4) is also known as peroxisomal multifunctional enzyme/protein 2 (MFE-2/MFP-2)
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission743nm/767nm
Synonyms MFE-2 DBP SDR8C1
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
ConjugatedThese antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths
Gene targetHSD17B4 Conjugated
Short name Conjugated, HSD17B4 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy7
Alternative name cyanine 7 coupled, HSD17B4 (Antibody to)
Alternative techniqueantibodies
Identity 5213
Gene HSD17B4
Long gene name hydroxysteroid 17-beta dehydrogenase 4
Synonyms gene name hydroxysteroid (17-beta) dehydrogenase 4
Synonyms name 17beta-estradiol dehydrogenase type IV peroxisomal multifunctional protein 2 17-beta-HSD IV 17-beta-hydroxysteroid dehydrogenase 4 D-bifunctional protein, member 1 , peroxisomal D-3-hydroxyacyl-CoA dehydratase 3-alpha, 12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase beta-keto-reductase beta-hydroxyacyl dehydrogenase short chain dehydrogenase/reductase family 8C, 7-alpha
Locus 5q23, 1
Discovery year 1994-09-14
Entrez gene record 3295
Pubmed identfication 8938456 19027726
RefSeq identity NM_000414
Classification Short chain dehydrogenase/reductase superfamily
Havana BLAST/BLAT OTTHUMG00000128899

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