Name : HSD17B8 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN2634630677
| Long name | HSD17B8 Primary Polyclonal Antibody |
| Also known as | HSD17B8 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | HSD17B8 |
| Specificity | This is a highly specific antibody against HSD17B8 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human HSD17B8 |
| Gene ID number | 7923 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | 17beta-HSD8 converts active steroids to their inactive form through its oxidative activity, 17beta-HSD8 is predominantly expressed in placenta, It has also been suggested that low levels of 17beta-HSD proteins may result in an underdeveloped urogenital system, It has been proposed that a reduction in the levels of 17beta-HSD8 may lead to abnormal elevations in the local level of sex steroids, It is a key player in the inactivation of Estradiol and Testosterone, and pancreas, endometrium and prostate but can also be found in liver, ovary and kidney, which can lead to recessive renal cystic disease, with lowest levels found in testis, 17beta-HSD8 belongs to the 17beta-HSD family of proteins that regulate the availability of steroids within a tissue |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | 17 beta hydroxysteroid dehydrogenase 8, 17-beta-HSD 8, 17-beta-hydroxysteroid dehydrogenase 8, 17beta hydroxysteroid dehydrogenase type 8, 3-oxoacyl-[acyl-carrier-protein] reductase, Beta ketoacyl [acyl carrier protein] reductase like, D6S2245E, DHB8_HUMAN, Estradiol 17 beta dehydrogenase 8, Estradiol 17-beta-dehydrogenase 8, Estrogen 17 oxidoreductase, FABG, FABGL, H2 KE6, HKE6, HSD17B8, Hydroxysteroid 17 beta dehydrogenase 8, KE6, Ke-6, Protein Ke6, RING2, Really interesting new gene 2 protein, SDR30C1, Short chain dehydrogenase/reductase family 30C member 1, Testosterone 17 beta dehydrogenase 8, Testosterone 17-beta-dehydrogenase 8, dJ1033B10, 17 beta HSD 8, 9 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | HSD17B8 |
| Short name | HSD17B8 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | HSD17B8 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 3554 |
| Gene | HSD17B8 |
| Long gene name | hydroxysteroid 17-beta dehydrogenase 8 |
| Synonyms gene | FABGL |
| Synonyms gene name | E coli) like (E, FabG (beta-ketoacyl-[acyl-carrier-protein] reductase, coli) hydroxysteroid (17-beta) dehydrogenase 8 |
| Synonyms | HKE6 D6S2245E RING2 KE6 H2-KE6 SDR30C1 |
| Synonyms name | member 1 , short chain dehydrogenase/reductase family 30C |
| Locus | 6p21, 32 |
| Discovery year | 2000-06-26 |
| GenBank acession | D82061 |
| Entrez gene record | 7923 |
| Pubmed identfication | 8812499 19027726 |
| RefSeq identity | NM_014234 |
| Classification | Short chain dehydrogenase/reductase superfamily |
| Havana BLAST/BLAT | OTTHUMG00000031117 |