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HSF1(Ser303) Antibody

HSF1(Ser303) Antibody size: 0.1ml 281

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 281
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameHSF1(Ser303) Primary Polyclonal Antibody
Also known asHSF1(Ser303) PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenHSF1 Ser303
SpecificityThis is a highly specific antibody against HSF1 Ser303
Modification(s)Phosphorylation
Modification site(s)Ser303
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human HSF1 around the phosphorylation site of Ser303
Gene ID number3297
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen HSF 1 and HSF 2, HSF 1 becomes activated to a nuclear localized, HSF 1 is responsive to classical stress signals such as heat, The phosphorylation of HSF 1 is necessary for maximal transcription of heat shock genes, These factors are activated by distinct stimuli, Through an unknown signal generated during stress, heavy metals and oxidative reagents, trimeric state which binds to DNA, whereas HSF 2 is activated during hemin-mediated differentiation of human erythroleukemia cells, which bind to the same HSEs and have 38% sequence identity, HSF 1 exists constitutively in the cytoplasm and the nucleus of unstressed cells as a monomer which lacks DNA binding activity, Two HSFs have been identified in human cells
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names HSF 1, HSTF 1, HSTF1, Heat shock factor 1, Heat shock factor protein 1, Heat shock transcription factor 1, hsf1, HSF1Ser303
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetHSF1(Ser303)
Short nameHSF1(Ser303) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameheat shock transcription factor 1(Ser303) (Antibody to)
Alternative techniqueantibodies
Alternative to gene target DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0006468 and protein phosphorylation and biological process this GO :0006952 and defense response and biological process this GO :0007143 and female meiotic division and biological process this GO :0007283 and spermatogenesis and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0009408 and response to heat and biological process this GO :0032496 and response to lipopolysaccharide and biological process this GO :0032720 and negative regulation of tumor necrosis factor production and biological process this GO :0034605 and cellular response to heat and biological process this GO :0040018 and positive regulation of multicellular organism growth and biological process this GO :0043234 and protein complex and cellular component this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0045120 and pronucleus and cellular component this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0060136 and embryonic process involved in female pregnancy and biological process this GO :0090231 and regulation of spindle checkpoint and biological process, HSF1 and IDBG-40498 and ENSG00000185122 and 3297, HSF1 and IDBG-643592 and ENSBTAG00000020751 and 506235, HSTF1, Hsf1 and IDBG-155311 and ENSMUSG00000022556 and 15499, nuclei, sequence-specific DNA binding, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0000978 and RNA polymerase II core promoter proximal region sequence-specific DNA binding and molecular function this GO :0001078 and RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription and molecular function this GO :0001162 and RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding and molecular function this GO :0001701 and in utero embryonic development and biological process this GO :0001892 and embryonic placenta development and biological process this GO :0003677 and DNA binding and molecular function this GO :0003682 and chromatin binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006351 and transcription, this GO :0000978: RNA polymerase II core promoter proximal region sequence-specific DNA binding, this GO :0000978: RNA polymerase II core promoter proximal region sequence-specific DNA binding and also this GO :0001078: RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription and also this GO :0001162: RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding and also this GO :0003677: DNA binding and also this GO :0003682: chromatin binding and also this GO :0003700: sequence-specific DNA binding transcription factor activity and also this GO :0005515: protein binding and also this GO :0043565: sequence-specific DNA binding, this GO :0001078: RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, this GO :0001162: RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding, this GO :0003677: DNA binding, this GO :0003682: chromatin binding, this GO :0003700: sequence-specific DNA binding transcription factor activity, this GO :0005515: protein binding, this GO :0043565: sequence-specific DNA binding, heat shock transcription factor 1
Identity 5224
Gene HSF1
Long gene name heat shock transcription factor 1
Synonyms HSTF1
Locus 8q24, 3
Discovery year 1994-09-12
GenBank acession M64673
Entrez gene record 3297
Pubmed identfication 1871105
RefSeq identity NM_005526
Havana BLAST/BLAT OTTHUMG00000174604

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