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HSP27(Ser78) Antibody

HSP27(Ser78) Antibody size: 0.1ml 281

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 281
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameHSP27(Ser78) Primary Polyclonal Antibody
Also known asHSP27(Ser78) PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenHSP27 Ser78
Specificity This phosphorylation does not exist in Mouse and Rat due to an asparagine substitution at this position, This is a highly specific antibody against HSP27 Ser78
Modification(s)Phosphorylation
Modification site(s)Ser78
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range50-100/205
Subcellular location Nucleus, Cytoplasm
SourceKLH conjugated synthetic phosphopeptide derived from human HSP27 around the phosphorylation site of Ser78
Gene ID number3315
Swiss ProtP04792
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivityHuman
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Because of the estrogen responsive nature of Hsp27, Hsp27 synthesis is induced by elevated temperature, Interestingly, This protein is involved in stress resistance and actin organization, This work has led to the suggestion that Hsp27 may be a useful marker in classifying various hormone sensitive tumors, also referred to as the Estrogen regulated 24K protein and HSP28, as well as estrogen in hormone responsive cells, endometrium and breast tissue, human HSP27 also shares greater than 50% homology with low molecular weight Drosophila HSP's and mammalian a-crystalline lens protein, is one of several small heat shock proteins (HSP) produced by all organisms studied, this protein has been studied extensively in human estrogen responsive tissues such as cervix, Hsp27
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names 28 kDa heat shock protein, Estrogen-regulated 24 kDa protein, HEL-S-102, HMN2B, HS, HSP 27, HSP27, HSP28, Heat shock 27 kDa protein, Heat shock protein beta-1, Hsp25, HspB1, SRP27, Stress-responsive protein 27, 76067, CMT2F
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetHSP27(Ser78)
Short nameHSP27(Ser78) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameHSP27(Ser78) (Antibody to)
Alternative techniqueantibodies
Identity 5246
Gene HSPB1
Long gene name heat shock protein family B (small) member 1
Synonyms gene name heat shock 27kD protein 1 heat shock 27kDa protein 1
Synonyms HSP27 HSP28 Hs, 76067 Hsp25 CMT2F
Locus 7q11, 23
Discovery year 1991-07-09
GenBank acession X54079
Entrez gene record 3315
Pubmed identfication 2243808 9344682
Classification Small heat shock proteins
Havana BLAST/BLAT OTTHUMG00000023228
Locus Specific Databases Inherited Peripheral Neuropathies Mutation Database LRG_248

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