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HSP90 Antibody / HSP90AA1

HSP90 Antibody / HSP90AA1 size: 0.1mg 406

Supplier NJS POLY
Price 406
Size 0.1mg
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration2ml sterile DI water, 5mg/ml if reconstituted with 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenHSP90 / HSP90AA1
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ICC, IHC-P, WB
Recommended dilutions5-1ug/ml, 5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Immunocytochemistry: 0, Western blot: 0
Notes Titration of the HSP90 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting points
Intented useThis HSP90 antibodyis to be used only for research purposes and not for diagnostics
Gene ID #3320
PurityAntigen affinity
Description AKT, Although it is highly expressed in most cells, BCR-ABL, HSP90 acts as a capacitor for morphologic evolution through epigenetic and genetic mechanisms, HSP90 inhibitors selectively kill cancer cells compared to normal cells, Heat shock proteins, Inhibitors of it are investigated as anti-cancer drugs, It is a molecular chaperone that plays a key role in the conformational maturation of oncogenic signaling proteins, RAF1, and aids in protein degradation, and mutated p53, and the the inhibitor 17-allylaminogeldanamycin (17-AAG) exhibited antitumor activity in preclinical models, are among the most highly expressed cellular proteins across all species, as a class, including HER2/ERBB2, stabilizes proteins against heat stress, Heat shock protein 90 is a chaperone protein that assists other proteins to fold properly
ImmunogenHuman partial recombinant protein (AA 2-365) was used as the immunogen for this HSP90 antibody
Storage Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the HSP90 antibody can be stored for up to one month at 4oC, After reconstitution
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetHSP90 / HSP90AA1
Short nameHSP90 Antibody / HSP90AA1
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameHSP90 (Antibody to) / HSP90AA1
Alternative techniqueantibodies
Identity 5253
Gene HSP90AA1
Long gene name heat shock protein 90 alpha family class A member 1
Synonyms gene HSPC1 HSPCA
Synonyms gene name alpha heat shock 90kDa protein 1, alpha heat shock protein 90kDa alpha (cytosolic), class A member 1 , heat shock 90kD protein 1
Synonyms Hsp89 Hsp90 FLJ31884 HSP90N
Locus 14q32, 31
Discovery year 1990-06-27
GenBank acession M27024
Entrez gene record 3320
Pubmed identfication 2527334 16269234
RefSeq identity NM_005348
Classification Heat shock 90kDa proteins
Havana BLAST/BLAT OTTHUMG00000171752

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