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HSPABP/HIP/HSC70 Interacting Protein HIP Antibody, FITC Conjugated

HSPABP/HIP/HSC70 Interacting Protein HIP Antibody, FITC Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, HSPABP/HIP/HSC70 Interacting Protein HIP Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenHSPABP/HIP/HSC70 Interacting Protein HIP
SpecificityThis is a highly specific antibody against HSPABP/HIP/HSC70 Interacting Protein HIP
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human HSPABP
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background By collaborating with other positive co-factors such as HSP40 and Hop, Hip directly binds to the ATPase domain of HSP70 when it is converted to the ADP-bound state by proteins of the HSP40 family (3), Hip may facilitate the chaperone function of HSP70 in protein folding and repair, The homo-oligomeric protein Hip cooperates with HSP70 in protein folding by stabilizing the ADP-bound state of HSP70, also known as ST13 (suppression of tumorigenicity protein 13), and in controlling the activity of regulatory proteins such as steroid receptors and various regulators of proliferation or apoptosis (4-8), is one of several co-chaperones that regulate activities of the HSP70 chaperone family (1, or competing with negative co-factors such as Bag1, 2), Hip (HSP70-interacting protein)
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms HSC71 HSC70 HSP73
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetHSPABP/HIP/HSC70 Interacting Protein HIP Conjugated
Short name FITC Conjugated, HSPABP/HIP/HSC70 Interacting Protein HIP Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, HSPABP/HIP/HSC70 Interacting Protein HIP (Antibody to)
Alternative techniqueantibodies
Identity 5241
Gene HSPA8
Long gene name heat shock protein family A (Hsp70) member 8
Synonyms gene HSPA10
Synonyms gene name heat shock 70kD protein 8 heat shock 70kDa protein 8
Locus 11q24, 1
Discovery year 1995-05-08
GenBank acession Y00371
Entrez gene record 3312
Pubmed identfication 8530083 3037489
Classification NineTeen complex Heat shock 70kDa proteins
Havana BLAST/BLAT OTTHUMG00000166030

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