| Long name | DRB1-4 beta chain (HLA-DRB1), Recombinant Human HLA class II histocompatibility antigen |
| Alternative names | DR beta 4, DR beta 4, DR beta 4 chain, DR-4, DR4, DRB1 transplantation antigen, DRB1-4 beta chain, DRB1-4 beta chain, HLA class II histocompatibility antigen, HLA class II histocompatibility antigen, MHC HLA DR-beta chain, MHC class II antigen DRB1*4, MHC class II antigen DRB4, MHC class II antigen HLA-DR-beta, MHC class2 antigen, class II, class II, human leucocyte antigen DRB4, leukocyte antigen, major histocompatibility complex, major histocompatibility complex, HLA class II histocompatibility antigen |
| Gene name | HLA-DRB1 |
| Other gene names | DR-4, DR-4, DR4, DR4, DRB4, HLA-DR4B, HLA-DRB1, HLA-DRB4 |
| General description | All of our recombinant proteins are manufactured in strictly controlled facilities and by using a well established technology which guarantees full batch-to-bact consistency and experiment reproducibility, DRB1-4 beta chain (HLA-DRB1) is a recombinant protein expressed in Baculovirus , The protein can be with or without a His-Tag or other tag in accordance to customer's request, HLA class II histocompatibility antigen |
| Product category | Recombinant Proteins |
| Expression system | Baculovirus |
| Available also expressed in: | Baculovirus , Mammalian Cell, Yeast , E Coli |
| Purity | Greater than 90% (determined by SDS-PAGE) |
| Form | Lyophilized protein |
| Storage | Avoid cycles of freezing and thawing as they might denaturate the polypeptide chains, For extended periods of time it is recommended to keep the protein frozen at -40 or -80 degrees Celsius, This protein can be stored at -20 degrees Celsius |
| Applications | IFA, RIA, Western Blot, etc, This protein can be used as a positive control for applications such as ELISA |
| Description | Antigens are peptides or recombinant or native dependent on the production method |
| Properties | Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, Homo sapiens sapiens), Human proteins, humans , ssp |
| Gene target | HLA class II histocompatibility DRB1-4 beta chain (HLA-DRB1) |
| Short name | DRB1-4 beta chain (HLA-DRB1), HLA class II histocompatibility antigen |
| Technique | antigenes, antigen |
| Species | Humans, Human |
| Alternative name | DR b 1), DRB1-4 b epitope (major histocompatibility aggregate, class II, sapiens Human leukocyte antigen class II histocompatibility protein, H |
| Alternative technique | antigenes |
| Alternative to gene target | Cell surfaces, DR beta 1, DRB1 and DRw10 and HLA-DR1B and HLA-DRB and SS1, HLA-DRB1 and IDBG-80863 and ENSG00000196126 and 100996809, class II, peptide antigen binding, this GO :0000139 and this GO lgi membrane and cellular component this GO :0002381 and immunoglobulin production involved in immunoglobulin mediated immune response and biological process this GO :0002437 and inflammatory response to antigenic stimulus and biological process this GO :0002455 and humoral immune response mediated by circulating immunoglobulin and biological process this GO :0002506 and polysaccharide assembly with MHC class II protein complex and biological process this GO :0005515 and protein binding and molecular function this GO :0005765 and lysosomal membrane and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006955 and immune response and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0009986 and cell surface and cellular component this GO :0012507 and ER to this GO lgi transport vesicle membrane and cellular component this GO :0016020 and membrane and cellular component this GO :0016045 and detection of bacterium and biological process this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0019882 and antigen processing and presentation and biological process this GO :0019886 and antigen processing and presentation of exogenous peptide antigen via MHC class II and biological process this GO :0023026 and MHC class II protein complex binding and molecular function this GO :0030658 and transport vesicle membrane and cellular component this GO :0030666 and endocytic vesicle membrane and cellular component this GO :0030669 and clathrin-coated endocytic vesicle membrane and cellular component this GO :0031295 and T cell costimulation and biological process this GO :0031902 and late endosome membrane and cellular component this GO :0032395 and MHC class II receptor activity and molecular function this GO :0032588 and trans- this GO lgi network membrane and cellular component this GO :0032673 and regulation of interleukin-4 production and biological process this GO :0032689 and negative regulation of interferon-gamma production and biological process this GO :0035774 and positive regulation of insulin secretion involved in cellular response to glucose stimulus and biological process this GO :0042088 and T-helper 1 type immune response and biological process this GO :0042130 and negative regulation of T cell proliferation and biological process this GO :0042605 and peptide antigen binding and molecular function this GO :0042613 and MHC class II protein complex and cellular component this GO :0050852 and T cell receptor signaling pathway and biological process this GO :0051262 and protein tetramerization and biological process this GO :0060333 and interferon-gamma-mediated signaling pathway and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0071556 and integral component of lumenal side of endoplasmic reticulum membrane and cellular component this GO :2001179 and regulation of interleukin-10 secretion and biological process, this GO :0005515: protein binding, this GO :0005515: protein binding and also this GO :0023026: MHC class II protein complex binding and also this GO :0032395: MHC class II receptor activity and also this GO :0042605: peptide antigen binding, this GO :0023026: MHC class II protein complex binding, this GO :0032395: MHC class II receptor activity, this GO :0042605: peptide antigen binding, 3123, major histocompatibility complex |
| Identity | 4948 |
| Gene | HLA-DRB1 |
| Long gene name | DR beta 1 , class II, major histocompatibility complex |
| Synonyms gene | HLA-DR1B |
| Locus | 6p21, 32 |
| Discovery year | 2001-06-22 |
| GenBank acession | AJ297583 |
| Entrez gene record | 3123 |
| RefSeq identity | NM_002124 |
| Classification | C1-set domain containing Histocompatibility complex |
| Havana BLAST/BLAT | OTTHUMG00000031196 |
| Locus Specific Databases | IMGT/HLA Database |
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