| Long name | ICAM1 Primary Polyclonal Antibody |
| Also known as | ICAM1 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | ICAM1 |
| Specificity | This is a highly specific antibody against ICAM1 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 220-270/537 |
| Subcellular location | Extracellular |
| Source | KLH conjugated synthetic peptide derived from mouse ICAM1 |
| Gene ID number | 15894 |
| Swiss Prot | P13597 |
| Tested Applications | IF(ICC), IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(ICC)(1:50-200), IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Rat, Mouse |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation (By similarity), ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2) |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | Icam-1, Icam1, Intercellular adhesion molecule 1, Ly-47, MALA-2, MyD1, CD54 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | ICAM1 |
| Short name | ICAM1 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | intercellular adhesion molecule 1 (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | BB2 and CD54 and P3, Extracellular, ICAM1 and IDBG-26804 and ENSG00000090339 and 3383, ICAM1 and IDBG-643247 and ENSBTAG00000010303 and 281839, Icam1 and IDBG-138668 and ENSMUSG00000037405 and 15894, protein complex binding, this GO :0001541 and ovarian follicle development and biological process this GO :0001618 and virus receptor activity and molecular function this GO :0001666 and response to hypoxia and biological process this GO :0001772 and immunological synapse and cellular component this GO :0001910 and regulation of leukocyte mediated cytotoxicity and biological process this GO :0001975 and response to amphetamine and biological process this GO :0002291 and T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell and biological process this GO :0002438 and acute inflammatory response to antigenic stimulus and biological process this GO :0002457 and T cell antigen processing and presentation and biological process this GO :0002693 and positive regulation of cellular extravasation and biological process this GO :0004872 and receptor activity and molecular function this GO :0004888 and transmembrane signaling receptor activity and molecular function this GO :0005178 and integrin binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005615 and extracellular space and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0007155 and cell adhesion and biological process this GO :0007157 and heterophilic cell-cell adhesion and biological process this GO :0007159 and leukocyte cell-cell adhesion and biological process this GO :0007569 and cell aging and biological process this GO :0007605 and sensory perception of sound and biological process this GO :0008360 and regulation of cell shape and biological process this GO :0009615 and response to virus and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0009986 and cell surface and cellular component this GO :0010212 and response to ionizing radiation and biological process this GO :0010477 and response to sulfur dioxide and biological process this GO :0014070 and response to organic cyclic compound and biological process this GO :0016020 and membrane and cellular component this GO :0016337 and single organismal cell-cell adhesion and biological process this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0022614 and membrane to membrane docking and biological process this GO :0030155 and regulation of cell adhesion and biological process this GO :0030198 and extracellular matrix organization and biological process this GO :0030838 and positive regulation of actin filament polymerization and biological process this GO :0031669 and cellular response to nutrient levels and biological process this GO :0032321 and positive regulation of Rho GTPase activity and biological process this GO :0032403 and protein complex binding and molecular function this GO :0032496 and response to lipopolysaccharide and biological process this GO :0033627 and cell adhesion mediated by integrin and biological process this GO :0034698 and response to this GO nadotropin and biological process this GO :0042493 and response to drug and biological process this GO :0043200 and response to amino acid and biological process this GO :0044406 and adhesion of symbiont to host and biological process this GO :0045087 and innate immune response and biological process this GO :0045429 and positive regulation of nitric oxide biosynthetic process and biological process this GO :0045471 and response to ethanol and biological process this GO :0045907 and positive regulation of vasoconstriction and biological process this GO :0046688 and response to copper ion and biological process this GO :0046813 and receptor-mediated virion attachment to host cell and biological process this GO :0050731 and positive regulation of peptidyl-tyrosine phosphorylation and biological process this GO :0050776 and regulation of immune response and biological process this GO :0050900 and leukocyte migration and biological process this GO :0051092 and positive regulation of NF-kappaB transcription factor activity and biological process this GO :0051926 and negative regulation of calcium ion transport and biological process this GO :0060333 and interferon-gamma-mediated signaling pathway and biological process this GO :0061028 and establishment of endothelial barrier and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070374 and positive regulation of ERK1 and ERK2 cascade and biological process this GO :0071222 and cellular response to lipopolysaccharide and biological process this GO :0071310 and cellular response to organic substance and biological process this GO :0071312 and cellular response to alkaloid and biological process this GO :0071333 and cellular response to glucose stimulus and biological process this GO :0071347 and cellular response to interleukin-1 and biological process this GO :0071356 and cellular response to tumor necrosis factor and biological process this GO :0071456 and cellular response to hypoxia and biological process this GO :0097368 and establishment of Sertoli cell barrier and biological process this GO :1900027 and regulation of ruffle assembly and biological process this GO :1902042 and negative regulation of extrinsic apoptotic signaling pathway via death domain receptors and biological process this GO :2000352 and negative regulation of endothelial cell apoptotic process and biological process, this GO :0001618: virus receptor activity, this GO :0001618: virus receptor activity and also this GO :0004872: receptor activity and also this GO :0004888: transmembrane signaling receptor activity and also this GO :0005178: integrin binding and also this GO :0005515: protein binding and also this GO :0032403: protein complex binding, this GO :0004872: receptor activity, this GO :0004888: transmembrane signaling receptor activity, this GO :0005178: integrin binding, this GO :0005515: protein binding, this GO :0032403: protein complex binding, 58, intercellular adhesion molecule 1 |
| Identity | 5344 |
| Gene | ICAM1 |
| Long gene name | intercellular adhesion molecule 1 |
| Synonyms | BB2 CD54 |
| Synonyms name | human rhinovirus receptor |
| Locus | 19p13, 2 |
| Discovery year | 1989-04-24 |
| Entrez gene record | 3383 |
| Pubmed identfication | 2453850 3871395 |
| Classification | Endogenous ligands CD molecules Immunoglobulin like domain containing |
| Havana BLAST/BLAT | OTTHUMG00000180403 |