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ICOS/CD278 Antibody, HRP Conjugated

ICOS/CD278 Antibody, HRP Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name HRP Conjugated, ICOS/CD278 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationHRP Conjugated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenICOS/CD278
Specificity This antibody may also have a secondary cross-reactivity with AP-1 complex-associated regulatory protein due to a 77% non-contiguous sequence similarity in the corresponding immunogen region, This is a highly specific antibody against ICOS/CD278
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range40-90/199
Subcellular locationExtracellular
SourceKLH conjugated synthetic peptide derived from human ICOS
Gene ID number29851
Swiss ProtQ9Y6W8
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Does not up-regulate the production of interleukin-2, Essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens, Plays a critical role in CD40-mediated class switching of immunoglobin isotypes (By similarity), Prevents the apoptosis of pre-activated T-cells, and effective help for antibody secretion by B-cells, but superinduces the synthesis of interleukin-10, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, Enhances all basic T-cell responses to a foreign antigen
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% Gentamicin, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms AILIM CD278
Properties Also monoclonal HRP conjugates are often used for Western Blot, HRP conjugates are often primary rabbit polyclonal antibodies couples to the , found in the roots of , (HRP), C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°, enzyme , horseradish, horseradish peroxidase 
Gene targetICOS/CD278 Conjugated
Short name Conjugated, ICOS/CD278 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelHRP
Alternative name horseradish peroxidase coupled, inducible T-cell co-stimulator/CD278 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target Extracellular, ICOS and IDBG-643378 and ENSBTAG00000021596 and 507026, ICOS and IDBG-79246 and ENSG00000163600 and 29851, Icos and IDBG-159737 and ENSMUSG00000026009 and 54167, protein binding, this GO :0002517 and T cell tolerance induction and biological process this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006955 and immune response and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0016337 and single organismal cell-cell adhesion and biological process this GO :0031295 and T cell costimulation and biological process, this GO :0005515: protein binding, this GO :0005515: protein binding, inducible T-cell co-stimulator
Identity 5351
Gene ICOS
Long gene name inducible T-cell costimulator
Synonyms name activation-inducible lymphocyte immunomediatory molecule
Locus 2q33, 2
Discovery year 2000-02-29
GenBank acession AB023135
Entrez gene record 29851
Pubmed identfication 9930702 10617205
RefSeq identity NM_012092
Classification CD molecules
Havana BLAST/BLAT OTTHUMG00000132880
Locus Specific Databases ICOSbase: Mutation registry for ICOS deficiency LRG_65

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