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ICOS-L/B7-H2/CD275 Antibody

ICOS-L/B7-H2/CD275 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameICOS-L/B7-H2/CD275 Primary Polyclonal Antibody
Also known asICOS-L/B7-H2/CD275 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenICOS-L/B7-H2/CD275
SpecificityThis is a highly specific antibody against ICOS-L/B7-H2/CD275
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range1-50/302
Subcellular locationCell membrane
SourceKLH conjugated synthetic peptide derived from Rat ICOS-L
Gene ID number23308
Swiss ProtO75144
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivityRat
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Acts as a costimulatory signal for T-cell proliferation and cytokine secretion, Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function (By similarity), induces also B-cell proliferation and differentiation into plasma cells, Ligand for the T-cell-specific cell surface receptor ICOS
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names B7 homolog 2, B7-H2, B7-like protein Gl50, B7-related protein 1, B7RP-1, B7RP1, CD275, GL50, ICOS ligand, ICOS-L, ICOSL, ICOSLG, KIAA0653, LICOS, B7H2
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetICOS-L/B7-H2/CD275
Short nameICOS-L/B7-H2/CD275 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameinducible T-cell co-stimulator-L/B7-H2/CD275 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target Extracellular, ICOS and IDBG-643378 and ENSBTAG00000021596 and 507026, ICOS and IDBG-79246 and ENSG00000163600 and 29851, Icos and IDBG-159737 and ENSMUSG00000026009 and 54167, protein binding, this GO :0002517 and T cell tolerance induction and biological process this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006955 and immune response and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0016337 and single organismal cell-cell adhesion and biological process this GO :0031295 and T cell costimulation and biological process, this GO :0005515: protein binding, this GO :0005515: protein binding, inducible T-cell co-stimulator
Identity 17087
Gene ICOSLG
Long gene name inducible T-cell costimulator ligand
Synonyms gene ICOSL
Synonyms KIAA0653 GL50 B7-H2 B7RP-1 B7H2 B7RP1 ICOS-L CD275
Synonyms name B7-related protein 1 B7 homologue 2 B7 homolog 2
Locus 21q22, 3
Discovery year 2003-12-12
GenBank acession AB014553
Entrez gene record 23308
Pubmed identfication 9734811 11007762
RefSeq identity NM_015259
Classification Endogenous ligands C2-set domain containing CD molecules V-set domain containing
Havana BLAST/BLAT OTTHUMG00000086920

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