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ICOS ligand Antibody

ICOS ligand Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameICOS ligand Primary Polyclonal Antibody
Also known asICOS ligand PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenICOS ligand
Specificity This antibody may have a secondary cross-reactivity to ", based upon a 67% sequence similarity, This is a highly specific antibody against ICOS ligand, similar to B7-like protein GL50-B"
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range80-130/322
Subcellular locationExtracellular
SourceKLH conjugated synthetic peptide derived from mouse ICOS-L
Gene ID number23308
Swiss ProtO75144
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivityMouse
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Acts as a costimulatory signal for T-cell proliferation and cytokine secretion, Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function (By similarity), induces also B-cell proliferation and differentiation into plasma cells, Ligand for the T-cell-specific cell surface receptor ICOS
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names B7 homolog 2, B7-H2, B7-like protein Gl50, B7-related protein 1, B7RP-1, B7RP1, CD275, GL50, ICOS ligand, ICOS-L, ICOSL, ICOSLG, KIAA0653, LICOS, B7H2
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetICOS ligand
Short nameICOS ligand Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameinducible T-cell co-stimulator ligand (Antibody to)
Alternative techniqueantibodies
Alternative to gene target Extracellular, ICOS and IDBG-643378 and ENSBTAG00000021596 and 507026, ICOS and IDBG-79246 and ENSG00000163600 and 29851, Icos and IDBG-159737 and ENSMUSG00000026009 and 54167, protein binding, this GO :0002517 and T cell tolerance induction and biological process this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006955 and immune response and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0016337 and single organismal cell-cell adhesion and biological process this GO :0031295 and T cell costimulation and biological process, this GO :0005515: protein binding, this GO :0005515: protein binding, inducible T-cell co-stimulator
Identity 5351
Gene ICOS
Long gene name inducible T-cell costimulator
Synonyms AILIM CD278
Synonyms name activation-inducible lymphocyte immunomediatory molecule
Locus 2q33, 2
Discovery year 2000-02-29
GenBank acession AB023135
Entrez gene record 29851
Pubmed identfication 9930702 10617205
RefSeq identity NM_012092
Classification CD molecules
Havana BLAST/BLAT OTTHUMG00000132880
Locus Specific Databases ICOSbase: Mutation registry for ICOS deficiency LRG_65

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