Name : IDE Antibody, ALEXA FLUOR 350
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN1241664670
| Long name | ALEXA FLUOR 350 Conjugated, IDE Polyclonal Antibody |
| Also known as | Anti-IDE PAb ALEXA FLUOR 350 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 350, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | IDE |
| Specificity | This is a highly specific antibody against IDE |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 514-564/1019 |
| Subcellular location | Cell membrane, Secreted, Cytoplasm |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human IDE |
| Gene ID Number | 3416 |
| Swiss Prot | P14735 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Degrades amyloid formed by APP and IAPP, IAPP, May play a role in the degradation and clearance of naturally secreted amyloid beta-protein by neurons and microglia, and thereby plays a role in intercellular peptide signaling, bradykinin, glucagon, kallidin and other peptides, Plays a role in the cellular breakdown of insulin |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 343nm/442nm |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | ALEXA FLUOR 350, Alexa Fluor |
| Gene target | IDE |
| Short name | IDE Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 350 |
| Alternative name | ALEXA FLUOR 350, insulin-degrading enzyme (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | IDE and IDBG-637578 and ENSBTAG00000019759 and 523752, IDE and IDBG-82456 and ENSG00000119912 and 3416, INSULYSIN, Ide and IDBG-161417 and ENSMUSG00000056999 and 15925, metal ion binding, nuclei, this GO :0001540 and beta-amyloid binding and molecular function this GO :0001948 and glycoprotein binding and molecular function this GO :0003824 and catalytic activity and molecular function this GO :0004222 and metalloendopeptidase activity and molecular function this GO :0005102 and receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005615 and extracellular space and cellular component this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005777 and peroxisome and cellular component this GO :0005782 and peroxisomal matrix and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006200 and ATP catabolic process and biological process this GO :0006508 and proteolysis and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0008286 and insulin receptor signaling pathway and biological process this GO :0008340 and determination of adult lifespan and biological process this GO :0009986 and cell surface and cellular component this GO :0010815 and bradykinin catabolic process and biological process this GO :0010992 and ubiquitin homeostasis and biological process this GO :0016032 and viral process and biological process this GO :0016887 and ATPase activity and molecular function this GO :0017046 and peptide hormone binding and molecular function this GO :0031597 and cytosolic proteasome complex and cellular component this GO :0031626 and beta-endorphin binding and molecular function this GO :0032461 and positive regulation of protein oli this GO merization and biological process this GO :0042277 and peptide binding and molecular function this GO :0042447 and hormone catabolic process and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0043130 and ubiquitin binding and molecular function this GO :0043559 and insulin binding and molecular function this GO :0044257 and cellular protein catabolic process and biological process this GO :0045861 and negative regulation of proteolysis and biological process this GO :0046872 and metal ion binding and molecular function this GO :0050435 and beta-amyloid metabolic process and biological process this GO :0051260 and protein homooli this GO merization and biological process this GO :0051289 and protein homotetramerization and biological process this GO :0051291 and protein heterooli this GO merization and biological process this GO :0051603 and proteolysis involved in cellular protein catabolic process and biological process this GO :1901142 and insulin metabolic process and biological process this GO :1901143 and insulin catabolic process and biological process, this GO :0001540: beta-amyloid binding, this GO :0001540: beta-amyloid binding and also this GO :0001948: glycoprotein binding and also this GO :0003824: catalytic activity and also this GO :0004222: metalloendopeptidase activity and also this GO :0005102: receptor binding and also this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0008270: zinc ion binding and also this GO :0016887: ATPase activity and also this GO :0017046: peptide hormone binding and also this GO :0031626: beta-endorphin binding and also this GO :0042277: peptide binding and also this GO :0042803: protein homodimerization activity and also this GO :0043130: ubiquitin binding and also this GO :0043559: insulin binding and also this GO :0046872: metal ion binding, this GO :0001948: glycoprotein binding, this GO :0003824: catalytic activity, this GO :0004222: metalloendopeptidase activity, this GO :0005102: receptor binding, this GO :0005515: protein binding, this GO :0005524: ATP binding, this GO :0008270: zinc ion binding, this GO :0016887: ATPase activity, this GO :0017046: peptide hormone binding, this GO :0031626: beta-endorphin binding, this GO :0042277: peptide binding, this GO :0042803: protein homodimerization activity, this GO :0043130: ubiquitin binding, this GO :0043559: insulin binding, this GO :0046872: metal ion binding, insulin-degrading enzyme |
| Identity | 5381 |
| Gene | IDE |
| Long gene name | insulin degrading enzyme |
| Synonyms gene name | insulin-degrading enzyme |
| Synonyms name | insulysin |
| Locus | 10q23, 33 |
| Discovery year | 1990-07-03 |
| GenBank acession | M21188 |
| Entrez gene record | 3416 |
| Pubmed identfication | 2293021 |
| RefSeq identity | NM_004969 |
| Havana BLAST/BLAT | OTTHUMG00000018759 |