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IDH1 Antibody

IDH1 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameIDH1 Primary Polyclonal Antibody
Also known asIDH1 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenIDH1
SpecificityThis is a highly specific antibody against IDH1
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human IDH1/Isocitrate dehydrogenase
Gene ID number3417
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Ca2+ can bind to IDHC as a complex with isocitrate, During this process, IDHC catalyzes the third step of the citric acid cycle, IDHC is expressed in a wide range of species and also in organisms that lack a complete citric acid cycle, The IDHC enzyme is inactivated by phosphorylation at Ser-113 and contains a clasp-like domain wherein both polypeptide chains in the dimer interlock, The first step involves the oxidation of isocitrate to the intermediate oxalosuccinate, acting as a competitive inhibitor of Mg2+, either NADH or NADPH is produced along with CO2, forming ?ketoglutarate and CO2 in a two step reaction, which involves the oxidative decarboxylation of isocitrate, while the second step involves the production of ?ketoglutarate, The Isocitrate dehydrogenase cytoplasmic enzyme is a homodimer of 416 residues that belongs to the isocitrate and isopropylmalate dehydrogenases family
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names Cytosolic NADP-isocitrate dehydrogenase, ICDH, IDCD, IDH, IDHC, IDHC_HUMAN, IDP, IDPC, Idh1, Isocitrate dehydrogenase 1 NADP+ soluble, Isocitrate dehydrogenase [NADP] cytoplasmic, NADP dependent isocitrate dehydrogenase cytosolic, NADP dependent isocitrate dehydrogenase peroxisomal, NADP+-specic ICDH, Oxalosuccinate decarboxylase, PICD, Cytosolic NADP isocitrate dehydrogenase
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetIDH1
Short nameIDH1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameIDH1 (Antibody to)
Alternative techniqueantibodies
Identity 5382
Gene IDH1
Long gene name cytosolic , isocitrate dehydrogenase (NADP(+)) 1
Synonyms gene name isocitrate dehydrogenase 1 (NADP+), soluble isocitrate dehydrogenase 1 (NADP+)
Locus 2q34
Discovery year 2001-06-22
Entrez gene record 3417
RefSeq identity NM_005896
Havana BLAST/BLAT OTTHUMG00000132943
Locus Specific Databases LRG_610

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