IDH1 Antibody, Biotin Conjugated

IDH1 Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1

Price 333

Size 0.1ml

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Long name	Biotin Conjugated, IDH1 Polyclonal Antibody
Category	Conjugated Primary Antibodies
Conjugation	Biotinylated
Host Organism	Rabbit (Oryctolagus cuniculus)
Target Antigen	IDH1
Specificity	This is a highly specific antibody against IDH1
Modification	Unmodified
Modification site	None
Clonality	Polyclonal
Clone	Polyclonal antibody
Concentration	1ug per 1ul
Source	KLH conjugated synthetic peptide derived from human IDH1/Isocitrate dehydrogenase
Gene ID number	3417
Tested applications	IHC-P, WB
Recommended dilutions	IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity	Mouse, Rat, Human
Crossreactive species details	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background	Ca2+ can bind to IDHC as a complex with isocitrate, During this process, IDHC catalyzes the third step of the citric acid cycle, IDHC is expressed in a wide range of species and also in organisms that lack a complete citric acid cycle, The IDHC enzyme is inactivated by phosphorylation at Ser-113 and contains a clasp-like domain wherein both polypeptide chains in the dimer interlock, The first step involves the oxidation of isocitrate to the intermediate oxalosuccinate, acting as a competitive inhibitor of Mg2+, either NADH or NADPH is produced along with CO2, forming ?ketoglutarate and CO2 in a two step reaction, which involves the oxidative decarboxylation of isocitrate, while the second step involves the production of ?ketoglutarate, The Isocitrate dehydrogenase cytoplasmic enzyme is a homodimer of 416 residues that belongs to the isocitrate and isopropylmalate dehydrogenases family
Purification method	This antibody was purified via Protein A
Storage conditions	50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission	N/A
Properties	Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene target	IDH1 Conjugated
Short name	Conjugated, IDH1 Antibody
Technique	antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label	Biotin
Alternative name	biotinilated coupled, IDH1 (Antibody to)
Alternative technique	antibodies
Identity	5382
Gene	IDH1
Long gene name	cytosolic , isocitrate dehydrogenase (NADP(+)) 1
Synonyms gene name	isocitrate dehydrogenase 1 (NADP+), soluble isocitrate dehydrogenase 1 (NADP+)
Locus	2q34
Discovery year	2001-06-22
Entrez gene record	3417
RefSeq identity	NM_005896
Havana BLAST/BLAT	OTTHUMG00000132943
Locus Specific Databases	LRG_610

IDH1 Antibody, Biotin Conjugated

IDH1 Antibody, Biotin Conjugated size: 0.1ml 333

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