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IDH1 Antibody, Cy3 Conjugated

IDH1 Antibody, Cy3 Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Cy3 Conjugated, IDH1 Polyclonal Antibody
CategoryConjugated Primary Antibodies
Conjugationcy3 conjugation kit
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenIDH1
SpecificityThis is a highly specific antibody against IDH1
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human IDH1/Isocitrate dehydrogenase
Gene ID number3417
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Ca2+ can bind to IDHC as a complex with isocitrate, During this process, IDHC catalyzes the third step of the citric acid cycle, IDHC is expressed in a wide range of species and also in organisms that lack a complete citric acid cycle, The IDHC enzyme is inactivated by phosphorylation at Ser-113 and contains a clasp-like domain wherein both polypeptide chains in the dimer interlock, The first step involves the oxidation of isocitrate to the intermediate oxalosuccinate, acting as a competitive inhibitor of Mg2+, either NADH or NADPH is produced along with CO2, forming ?ketoglutarate and CO2 in a two step reaction, which involves the oxidative decarboxylation of isocitrate, while the second step involves the production of ?ketoglutarate, The Isocitrate dehydrogenase cytoplasmic enzyme is a homodimer of 416 residues that belongs to the isocitrate and isopropylmalate dehydrogenases family
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission512, 550nm/570, 615nm
Properties 1 of the IDH1 Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetIDH1 Conjugated
Short name Conjugated, IDH1 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy3
Alternative name cyanine 3 coupled, IDH1 (Antibody to)
Alternative techniqueantibodies
Identity 5382
Gene IDH1
Long gene name cytosolic , isocitrate dehydrogenase (NADP(+)) 1
Synonyms gene name isocitrate dehydrogenase 1 (NADP+), soluble isocitrate dehydrogenase 1 (NADP+)
Locus 2q34
Discovery year 2001-06-22
Entrez gene record 3417
RefSeq identity NM_005896
Havana BLAST/BLAT OTTHUMG00000132943
Locus Specific Databases LRG_610

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