| Long name | IFI16 Primary Polyclonal Antibody |
| Also known as | IFI16 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | I16 |
| Specificity | This is a highly specific antibody against I16 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human IFI16 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Alternatively spliced transcript variants encoding different isoforms have been found for this gene, It modulates p53 function, The encoded protein contains domains involved in DNA binding, The protein localizes to the nucleoplasm and nucleoli, and inhibits cell growth in the Ras/Raf signaling pathway, and interacts with p53 and retinoblastoma-1, and protein-protein interactions, transcriptional regulation, IFI16 is a member of the HIN-200 (hematopoietic interferon-inducible nuclear antigens with 200 amino acid repeats) family of cytokines |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | 16_HUMAN, Gamma interferon inducible protein 16, Gamma-interferon-inducible protein i16, Interferon gamma induced protein I 16, Interferon gamma inducible protein 16, Interferon-inducible myeloid dferentiation transcriptional activator, NGIP1, PYHIN2, i204, interferon activated gene 204, p204, I16 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | IFI16 |
| Short name | IFI16 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | gamma-inducible protein 16 (Antibody to), interferon |
| Alternative technique | antibodies |
| Alternative to gene target | DNA-templated and biological process this GO :0006914 and autophagy and biological process this GO :0006954 and inflammatory response and biological process this GO :0008134 and transcription factor binding and molecular function this GO :0008283 and cell proliferation and biological process this GO :0010506 and regulation of autophagy and biological process this GO :0016020 and membrane and cellular component this GO :0016607 and nuclear speck and cellular component this GO :0030097 and hemopoiesis and biological process this GO :0030099 and myeloid cell differentiation and biological process this GO :0030224 and monocyte differentiation and biological process this GO :0032481 and positive regulation of type I interferon production and biological process this GO :0032731 and positive regulation of interleukin-1 beta production and biological process this GO :0042149 and cellular response to glucose starvation and biological process this GO :0042771 and intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator and biological process this GO :0043392 and negative regulation of DNA binding and biological process this GO :0044822 and poly(A) RNA binding and molecular function this GO :0045071 and negative regulation of viral genome replication and biological process this GO :0045087 and innate immune response and biological process this GO :0045824 and negative regulation of innate immune response and biological process this GO :0045892 and negative regulation of transcription, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0051607 and defense response to virus and biological process this GO :0071479 and cellular response to ionizing radiation and biological process this GO :0072332 and intrinsic apoptotic signaling pathway by p53 class mediator and biological process this GO :0097202 and activation of cysteine-type endopeptidase activity and biological process this GO :2000117 and negative regulation of cysteine-type endopeptidase activity and biological process, IFI16 and IDBG-103852 and ENSG00000163565 and 3428, IFNGIP1 and PYHIN2, gamma-inducible protein 16, nuclei, poly(A) RNA binding, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0001819 and positive regulation of cytokine production and biological process this GO :0002218 and activation of innate immune response and biological process this GO :0003690 and double-stranded DNA binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005730 and nucleolus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006351 and transcription, this GO :0003690: double-stranded DNA binding, this GO :0003690: double-stranded DNA binding and also this GO :0005515: protein binding and also this GO :0008134: transcription factor binding and also this GO :0044822: poly(A) RNA binding, this GO :0005515: protein binding, this GO :0008134: transcription factor binding, this GO :0044822: poly(A) RNA binding, interferon |
| Identity | 5395 |
| Gene | IFI16 |
| Long gene name | interferon gamma inducible protein 16 |
| Synonyms | IFNGIP1 PYHIN2 |
| Locus | 1q23, 1 |
| Discovery year | 1993-09-29 |
| GenBank acession | M63838 |
| Entrez gene record | 3428 |
| Pubmed identfication | 1526658 7959953 |
| RefSeq identity | NM_005531 |
| Classification | Pyrin domain containing Pyrin and HIN domain family |
| Havana BLAST/BLAT | OTTHUMG00000037108 |
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