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IFI16 Antibody, FITC Conjugated

IFI16 Antibody, FITC Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name FITC Conjugated, IFI16 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenI16
SpecificityThis is a highly specific antibody against I16
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human IFI16
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
CrossreactivityHuman
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Alternatively spliced transcript variants encoding different isoforms have been found for this gene, It modulates p53 function, The encoded protein contains domains involved in DNA binding, The protein localizes to the nucleoplasm and nucleoli, and inhibits cell growth in the Ras/Raf signaling pathway, and interacts with p53 and retinoblastoma-1, and protein-protein interactions, transcriptional regulation, IFI16 is a member of the HIN-200 (hematopoietic interferon-inducible nuclear antigens with 200 amino acid repeats) family of cytokines
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms IFNGIP1 PYHIN2
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetIFI16 Conjugated
Short name FITC Conjugated, IFI16 Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, gamma-inducible protein 16 (Antibody to), interferon
Alternative techniqueantibodies
Alternative to gene target DNA-templated and biological process this GO :0006914 and autophagy and biological process this GO :0006954 and inflammatory response and biological process this GO :0008134 and transcription factor binding and molecular function this GO :0008283 and cell proliferation and biological process this GO :0010506 and regulation of autophagy and biological process this GO :0016020 and membrane and cellular component this GO :0016607 and nuclear speck and cellular component this GO :0030097 and hemopoiesis and biological process this GO :0030099 and myeloid cell differentiation and biological process this GO :0030224 and monocyte differentiation and biological process this GO :0032481 and positive regulation of type I interferon production and biological process this GO :0032731 and positive regulation of interleukin-1 beta production and biological process this GO :0042149 and cellular response to glucose starvation and biological process this GO :0042771 and intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator and biological process this GO :0043392 and negative regulation of DNA binding and biological process this GO :0044822 and poly(A) RNA binding and molecular function this GO :0045071 and negative regulation of viral genome replication and biological process this GO :0045087 and innate immune response and biological process this GO :0045824 and negative regulation of innate immune response and biological process this GO :0045892 and negative regulation of transcription, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0051607 and defense response to virus and biological process this GO :0071479 and cellular response to ionizing radiation and biological process this GO :0072332 and intrinsic apoptotic signaling pathway by p53 class mediator and biological process this GO :0097202 and activation of cysteine-type endopeptidase activity and biological process this GO :2000117 and negative regulation of cysteine-type endopeptidase activity and biological process, IFI16 and IDBG-103852 and ENSG00000163565 and 3428, IFNGIP1 and PYHIN2, gamma-inducible protein 16, nuclei, poly(A) RNA binding, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0001819 and positive regulation of cytokine production and biological process this GO :0002218 and activation of innate immune response and biological process this GO :0003690 and double-stranded DNA binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005730 and nucleolus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006351 and transcription, this GO :0003690: double-stranded DNA binding, this GO :0003690: double-stranded DNA binding and also this GO :0005515: protein binding and also this GO :0008134: transcription factor binding and also this GO :0044822: poly(A) RNA binding, this GO :0005515: protein binding, this GO :0008134: transcription factor binding, this GO :0044822: poly(A) RNA binding, interferon
Identity 5395
Gene IFI16
Long gene name interferon gamma inducible protein 16
Locus 1q23, 1
Discovery year 1993-09-29
GenBank acession M63838
Entrez gene record 3428
Pubmed identfication 1526658 7959953
RefSeq identity NM_005531
Classification Pyrin domain containing Pyrin and HIN domain family
Havana BLAST/BLAT OTTHUMG00000037108

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