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IFI30 Antibody, Biotin Conjugated

IFI30 Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, IFI30 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenI30
SpecificityThis is a highly specific antibody against I30
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human IFI30
Gene ID number10437
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background A lysosomal thiol reductase, Additionally, Cytosolic reduction is mediated enzymatically by thioredoxin, Efficient proteolysis requires denaturation, GILT, GILT is expressed constitutively in antigen-presenting cells and is induced by g-interferon in other cell types, GILT is synthesized as a precursor, In the endocytic pathway, T cell recognition of select exogenous and endogenous epitopes is dependent on tumor cell expression of GILT, The absence of GILT in melanomas alters antigen processing and the hierarchy of immunodominant epitope presentation, This process is catalyzed by a gamma-interferon-inducible thiol reductase (GILT), and following delivery to MHC class II-containing compartments (MIICs), and reduction of inter- and intrachain disulfide bonds, induced by acidic conditions within lysosomes, is optimally active at low pH and capable of catalyzing disulfide bond reduction both in vivo and in vitro, is processed to the mature form via cleavage of amino- and carboxy-terminal propeptides, reduction of protein disulfide bonds is important for the generation of MHC class II-peptide complexes, suggesting a potentially important role in antigen processing, Proteins internalized into the endocytic pathway are usually degraded
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms IFI-30 GILT IP30 MGC32056 IP-30
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetIFI30 Conjugated
Short name Conjugated, IFI30 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, gamma-inducible protein 30 (Antibody to), interferon
Alternative techniqueantibodies
Alternative to gene target Extracellular, GILT and IFI-30 and IP30, IFI30 and IDBG-281623 and ENSG00000216490 and 10437, IFI30 and IDBG-641754 and ENSBTAG00000018349 and 615930, Ifi30 and IDBG-164061 and ENSMUSG00000031838 and 65972, acting on a sulfur group of donors, acting on a sulfur group of donors, acting on a sulfur group of donors and molecular function this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0019886 and antigen processing and presentation of exogenous peptide antigen via MHC class II and biological process this GO :0030054 and cell junction and cellular component this GO :0042590 and antigen processing and presentation of exogenous peptide antigen via MHC class I and biological process this GO :0043202 and lysosomal lumen and cellular component this GO :0043231 and intracellular membrane-bounded organelle and cellular component this GO :0048147 and negative regulation of fibroblast proliferation and biological process this GO :0050821 and protein stabilization and biological process this GO :0055114 and oxidation-reduction process and biological process this GO :0060333 and interferon-gamma-mediated signaling pathway and biological process, gamma-inducible protein 30, oxidoreductase activity, this GO :0005576 and extracellular region and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005764 and lysosome and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0016667 and oxidoreductase activity, this GO :0016667: oxidoreductase activity, this GO :0016667: oxidoreductase activity, interferon
Identity 5398
Gene IFI30
Long gene name IFI30, lysosomal thiol reductase
Synonyms gene name interferon gamma inducible protein 30
Synonyms name gamma-interferon-inducible lysosomal thiol reductase interferon gamma-inducible protein 30 preproprotein legumaturain
Locus 19p13, 11
Discovery year 1999-12-09
GenBank acession J03909
Entrez gene record 10437
Pubmed identfication 3136170 10639150
RefSeq identity NM_006332
Havana BLAST/BLAT OTTHUMG00000183373

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