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IFI35 Antibody, FITC Conjugated

IFI35 Antibody, FITC Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, IFI35 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenI35
SpecificityThis is a highly specific antibody against I35
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human IFI35
Gene ID number3430
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background IFI-35 (Interferon-induced 35 kDa protein), IFI-35 is a leucine zipper protein that can form homodimers, IFI-35 is unable to be degraded by the proteasome, Localized to the nucleus and expressed in macrophages, Once complexed with Nmi, Upon induction by IFN-? IFI-35 associates with Nmi (N-Myc-interacting protein), also known as IFP35, but, cannot bind DNA, fibroblasts and epithelial cells, is a 286 amino acid interferon-induced protein, resulting in the formation of a high molecular weight complex that is thought to play a role in IFN-?signaling and cellular responses, suggesting that IFI-35 is protected from degradation only when needed by IFN-? Two isoforms of IFI-35 exist due to alternative splicing events, thereby controlling various events within the cell, unlike most leucine zipper proteins, The Interferon family of proteins are able to alter the expression of a variety of target genes
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms IFP35
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetIFI35 Conjugated
Short name FITC Conjugated, IFI35 Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, interferon-induced protein 35 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target IFI35 and IDBG-52075 and ENSG00000068079 and 3430, IFI35 and IDBG-640619 and ENSBTAG00000007389 and 510697, IFP35, Ifi35 and IDBG-212192 and ENSMUSG00000010358 and 70110, nuclei, protein binding, this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005829 and cytosol and cellular component this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0060337 and type I interferon signaling pathway and biological process, this GO :0005515: protein binding, this GO :0005515: protein binding, interferon-induced protein 35
Identity 5399
Gene IFI35
Long gene name interferon induced protein 35
Synonyms gene name interferon-induced protein 35
Locus 17q21, 31
Discovery year 1996-04-12
GenBank acession BC001356
Entrez gene record 3430
RefSeq identity NM_005533
Havana BLAST/BLAT OTTHUMG00000167720

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