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IFNAR1(Ser535+Ser538) Antibody

IFNAR1(Ser535+Ser538) Antibody size: 0.1ml 281

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 281
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameIFNAR1(Ser535+Ser538) Antibody
Also known asIFNAR1(Ser535+Ser538) Antibody
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenIFNAR1 Ser535 + Ser538
SpecificityThis is a highly specific antibody against IFNAR1 Ser535 + Ser538
Modification(s)Phosphorylation
Modification site(s)Ser535+Ser538
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range510-550/557
Subcellular locationCytoplasm
SourceKLH conjugated synthetic phosphopeptide derived from human IFNAR1 around the phosphorylation site of Ser535+Ser538
Gene ID number3454
Swiss ProtP17181
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Binding to type I IFNs triggers tyrosine phosphorylation of a number of proteins including JAKs, Can also transduce IFNB signals without the help of IFNAR2, Receptor for interferons alpha and beta, STAT proteins and IFNR alpha- and beta-subunits themselves, TYK2, and not activating the Jak-STAT pathway, Associates with IFNAR2 to form the type I interferon receptor
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names CRF2-1, Cytokine receptor class-II member 1, Cytokine receptor family 2 member 1, IFN-R-1, IFN-alpha-REC, IFN-alpha/beta receptor 1, IFNAR, IFNAR1, IFNBR, IFRC, Interferon alpha/beta receptor 1, Type I interferon receptor 1, AVP
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetIFNAR1(Ser535+Ser538)
Short nameIFNAR1(Ser535+Ser538) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative name b and omega) receptor 1(Ser535+Ser538) (Antibody to), interferon (a
Alternative techniqueantibodies
Alternative to gene target AVP and IFN-alpha-REC and IFNAR and IFNBR and IFRC, IFNAR1 and IDBG-2095 and ENSG00000142166 and 3454, IFNAR1 and IDBG-629846 and ENSBTAG00000021819 and 282257, Ifnar1 and IDBG-176038 and ENSMUSG00000022967 and 15975, Plasma membranes, beta and omega) receptor 1, protein binding, this GO :0004904 and interferon receptor activity and molecular function this GO :0004905 and type I interferon receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007259 and JAK-STAT cascade and biological process this GO :0009615 and response to virus and biological process this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0032729 and positive regulation of interferon-gamma production and biological process this GO :0042110 and T cell activation and biological process this GO :0045087 and innate immune response and biological process this GO :0045351 and type I interferon biosynthetic process and biological process this GO :0050718 and positive regulation of interleukin-1 beta secretion and biological process this GO :0051607 and defense response to virus and biological process this GO :0060337 and type I interferon signaling pathway and biological process this GO :0060338 and regulation of type I interferon-mediated signaling pathway and biological process, this GO :0004904: interferon receptor activity, this GO :0004904: interferon receptor activity and also this GO :0004905: type I interferon receptor activity and also this GO :0005515: protein binding, this GO :0004905: type I interferon receptor activity, this GO :0005515: protein binding, interferon (alpha
Identity 5432
Gene IFNAR1
Long gene name interferon alpha and beta receptor subunit 1
Synonyms gene IFNAR
Synonyms gene name beta and omega) receptor 1 , interferon (alpha
Synonyms IFRC
Locus 21q22, 11
Discovery year 1986-01-01
Entrez gene record 3454
Pubmed identfication 8181059
Classification Interferon receptors
Havana BLAST/BLAT OTTHUMG00000065126

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