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IFNAR1(Ser535+Ser538) Antibody, FITC Conjugated

IFNAR1(Ser535+Ser538) Antibody, FITC Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, IFNAR1(Ser535+Ser538) Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenIFNAR1 Ser535 + Ser538
SpecificityThis is a highly specific antibody against IFNAR1 Ser535 + Ser538
ModificationPhosphorylation
Modification siteSer535+Ser538
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range510-550/557
Subcellular locationCytoplasm
SourceKLH conjugated synthetic phosphopeptide derived from human IFNAR1 around the phosphorylation site of Ser535+Ser538
Gene ID number3454
Swiss ProtP17181
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Binding to type I IFNs triggers tyrosine phosphorylation of a number of proteins including JAKs, Can also transduce IFNB signals without the help of IFNAR2, Receptor for interferons alpha and beta, STAT proteins and IFNR alpha- and beta-subunits themselves, TYK2, and not activating the Jak-STAT pathway, Associates with IFNAR2 to form the type I interferon receptor
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms IFRC
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetIFNAR1(Ser535+Ser538) Conjugated
Short name FITC Conjugated, IFNAR1(Ser535+Ser538) Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name b and omega) receptor 1(Ser535+Ser538) (Antibody to), fluorecein coupled, interferon (a
Alternative techniqueantibodies
Alternative to gene target AVP and IFN-alpha-REC and IFNAR and IFNBR and IFRC, IFNAR1 and IDBG-2095 and ENSG00000142166 and 3454, IFNAR1 and IDBG-629846 and ENSBTAG00000021819 and 282257, Ifnar1 and IDBG-176038 and ENSMUSG00000022967 and 15975, Plasma membranes, beta and omega) receptor 1, protein binding, this GO :0004904 and interferon receptor activity and molecular function this GO :0004905 and type I interferon receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007259 and JAK-STAT cascade and biological process this GO :0009615 and response to virus and biological process this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0032729 and positive regulation of interferon-gamma production and biological process this GO :0042110 and T cell activation and biological process this GO :0045087 and innate immune response and biological process this GO :0045351 and type I interferon biosynthetic process and biological process this GO :0050718 and positive regulation of interleukin-1 beta secretion and biological process this GO :0051607 and defense response to virus and biological process this GO :0060337 and type I interferon signaling pathway and biological process this GO :0060338 and regulation of type I interferon-mediated signaling pathway and biological process, this GO :0004904: interferon receptor activity, this GO :0004904: interferon receptor activity and also this GO :0004905: type I interferon receptor activity and also this GO :0005515: protein binding, this GO :0004905: type I interferon receptor activity, this GO :0005515: protein binding, interferon (alpha
Identity 5432
Gene IFNAR1
Long gene name interferon alpha and beta receptor subunit 1
Synonyms gene IFNAR
Synonyms gene name beta and omega) receptor 1 , interferon (alpha
Locus 21q22, 11
Discovery year 1986-01-01
Entrez gene record 3454
Pubmed identfication 8181059
Classification Interferon receptors
Havana BLAST/BLAT OTTHUMG00000065126

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