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IGF-I Receptor beta Antibody

IGF-I Receptor beta Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameIGF-I Receptor beta Primary Polyclonal Antibody
Also known asIGF-I Receptor beta PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenIGF-I Receptor beta
SpecificityThis is a highly specific antibody against IGF-I Receptor beta
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human IGF-IR beta chain
Gene ID number3480
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Cleavage of the precursor generates alpha and beta subunits, It has tyrosine kinase activity, It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival, Jul 2008], The insulin-like growth factor I receptor plays a critical role in transformation events, [provided by RefSeq, This receptor binds insulin-like growth factor with a high affinity
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names CD221, CD221 antigen, IGF 1 receptor, IGF 1R, IGF I receptor, IGF I receptor beta, IGF1 Receptor, IGF1R, IGF1R beta, IGF1R_HUMAN, IGFIR, IGFIR beta, IGFIRC, Insulin like growth factor 1 receptor, Insulin like growth factor 1 receptor beta, Insulin like growth factor 1 receptor precursor, JTK13, MGC142170, MGC142172, GF 1R beta
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Description IGF-1 acts via specific receptor, IGF-1R, IGF-II, Insulin-like growth factor -1 shares structural homology with proinsulin and is mainly produced by liver, Raf/Ras and PI3K cascades, a heterodimeric tyrosine kinase receptor that signals to various second messenger pathways such as MAPK, insulin-like growth factors -1 and -2 are important regulators of signaling that mediates growth and metabolism in cells, IGF-I
Gene targetI Receptor beta
Short nameIGF-I Receptor beta Antibody
Technique antibodies against human proteins, antibodies for, igfs, Antibody
Alternative nameIGF-I Receptor b (Antibody to)
Alternative techniqueantibodies
Identity 11772
Gene TGFBR1
Long gene name transforming growth factor beta receptor 1
Synonyms gene MSSE ESS1
Synonyms gene name multiple self-healing squamous epithelioma transforming growth factor beta receptor I
Synonyms ALK-5 ACVRLK4 ALK5
Synonyms name 53kDa , activin A receptor type II-like kinase
Locus 9q22, 33
Discovery year 1993-09-30
Entrez gene record 7046
Pubmed identfication 1319842 8530052 21358634
Classification Type 1 receptor serine/threonine kinases
Havana BLAST/BLAT OTTHUMG00000020353
Locus Specific Databases Belgium , Ghent, LOVD - Center for Medical Genetics

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