Name : IGF-I Receptor beta Antibody, ALEXA FLUOR 555
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN5174797426
| Long name | ALEXA FLUOR 555 Conjugated, IGF-I Receptor beta Polyclonal Antibody |
| Also known as | Anti-IGF-I Receptor beta PAb ALEXA FLUOR 555 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 555, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | IGF-I Receptor beta |
| Specificity | This is a highly specific antibody against IGF-I Receptor beta |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human IGF-IR beta chain |
| Gene ID Number | 3480 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Cleavage of the precursor generates alpha and beta subunits, It has tyrosine kinase activity, It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival, Jul 2008], The insulin-like growth factor I receptor plays a critical role in transformation events, [provided by RefSeq, This receptor binds insulin-like growth factor with a high affinity |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 553nm/568nm |
| Synonyms | ALK-5 ACVRLK4 ALK5 |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | ALEXA FLUOR 555, Alexa Fluor |
| Description | IGF-1 acts via specific receptor, IGF-1R, IGF-II, Insulin-like growth factor -1 shares structural homology with proinsulin and is mainly produced by liver, Raf/Ras and PI3K cascades, a heterodimeric tyrosine kinase receptor that signals to various second messenger pathways such as MAPK, insulin-like growth factors -1 and -2 are important regulators of signaling that mediates growth and metabolism in cells, IGF-I |
| Gene target | I Receptor beta |
| Short name | IGF-I Receptor beta Antibody |
| Technique | antibodies against human proteins, antibodies for, igfs, Antibody |
| Label | ALEXA FLUOR 555 |
| Alternative name | ALEXA FLUOR 555, IGF-I Receptor b (Antibody to) |
| Alternative technique | antibodies |
| Identity | 11772 |
| Gene | TGFBR1 |
| Long gene name | transforming growth factor beta receptor 1 |
| Synonyms gene | MSSE ESS1 |
| Synonyms gene name | multiple self-healing squamous epithelioma transforming growth factor beta receptor I |
| Synonyms name | 53kDa , activin A receptor type II-like kinase |
| Locus | 9q22, 33 |
| Discovery year | 1993-09-30 |
| Entrez gene record | 7046 |
| Pubmed identfication | 1319842 8530052 21358634 |
| Classification | Type 1 receptor serine/threonine kinases |
| Havana BLAST/BLAT | OTTHUMG00000020353 |
| Locus Specific Databases | Belgium , Ghent, LOVD - Center for Medical Genetics |