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IGF II Antibody

IGF II Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameIGF II Primary Polyclonal Antibody
Also known asIGF II PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenIGF II
SpecificityThis is a highly specific antibody against IGF II
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range20-70/180
Subcellular locationSecreted
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human IGF II
Gene ID number3481
Swiss ProtP01344
Tested Applications IF(IHC-P), IHC-P
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Exhibits osteogenic properties by increasing osteoblast mitogenic activity through phosphoactivation of MAPK1 and MAPK3, IGF-II is influenced by placental lactogen and may play a role in fetal development, In vitro, Preptin undergoes glucose-mediated co-secretion with insulin, and acts as physiological amplifier of glucose-mediated insulin secretion, they are potent mitogens for cultured cells, The insulin-like growth factors possess growth-promoting activity
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names C11orf43, IGF2, Insulin-like growth factor II, PP1446, PP9974, Somatomedin-A, IGF-II
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Description IGF-1 acts via specific receptor, IGF-1R, IGF-II, Insulin-like growth factor -1 shares structural homology with proinsulin and is mainly produced by liver, Raf/Ras and PI3K cascades, a heterodimeric tyrosine kinase receptor that signals to various second messenger pathways such as MAPK, insulin-like growth factors -1 and -2 are important regulators of signaling that mediates growth and metabolism in cells, IGF-I
Gene targetII
Short nameIGF II Antibody
Technique antibodies against human proteins, antibodies for, igfs, Antibody
Alternative nameIGF II (Antibody to)
Alternative techniqueantibodies
Identity 9191
Gene POLR2D
Long gene name RNA polymerase II subunit D
Synonyms gene name polymerase (RNA) II (DNA directed) polypeptide D
Synonyms RBP4
Synonyms name RNA polymerase II subunit hsRBP4
Locus 2q14, 3
Discovery year 1993-12-07
GenBank acession U85510
Entrez gene record 5433
Pubmed identfication 9528765
RefSeq identity NM_004805
Classification RNA polymerase subunits
Havana BLAST/BLAT OTTHUMG00000131531

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