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IGF2BP3 Antibody

IGF2BP3 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameIGF2BP3 Primary Polyclonal Antibody
Also known asIGF2BP3 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenIGF2BP3
SpecificityThis is a highly specific antibody against IGF2BP3
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range110-170/579
Subcellular location Nucleus, Cytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Insulin-like growth factor 2 mRNA-binding protein 3
Gene ID number10643
Swiss ProtO00425
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Binds to beta-actin/ACTB and MYC transcripts, Binds to the 3'-UTR of CD44 mRNA and stabilizes it, Binds to the 5'-UTR of the insulin-like growth factor 2 (IGF2) mRNAs, It also modulates the rate and location at which target transcripts encounter the translational apparatus and shields them from endonuclease attacks or microRNA-mediated degradation, This transcript 'caging' into mRNPs allows mRNA transport and transient storage, hence promotes cell adhesion and invadopodia formation in cancer cells, RNA-binding factor that may recruits target transcripts to cytoplasmic protein-RNA complexes (mRNPs)
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names CT98, IGF-II mRNA-binding protein 3, IGF2 mRNA-binding protein 3, IGF2BP3, IMP-3, IMP3, Insulin-like growth factor 2 mRNA-binding protein 3, KH domain-containing protein overexpressed in cancer, KOC1, VICKZ family member 3, VICKZ3, hKOC, KOC
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetIGF2BP3
Short nameIGF2BP3 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameinsulin-like growth factor 2 messenger RNA binding protein 3 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target CT98 and IMP-3 and IMP3 and KOC and KOC1 and VICKZ3, IGF2BP3 and IDBG-630336 and ENSBTAG00000019406 and 539650, IGF2BP3 and IDBG-9675 and ENSG00000136231 and 10643, Igf2bp3 and IDBG-146190 and ENSMUSG00000029814 and 140488, mRNA 5'-UTR binding, nuclei, this GO :0000166 and nucleotide binding and molecular function this GO :0003676 and nucleic acid binding and molecular function this GO :0003723 and RNA binding and molecular function this GO :0003730 and mRNA 3'-UTR binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006412 and translation and biological process this GO :0009653 and anatomical structure morphogenesis and biological process this GO :0010467 and gene expression and biological process this GO :0017148 and negative regulation of translation and biological process this GO :0042035 and regulation of cytokine biosynthetic process and biological process this GO :0044822 and poly(A) RNA binding and molecular function this GO :0045182 and translation regulator activity and molecular function this GO :0048027 and mRNA 5'-UTR binding and molecular function this GO :0051028 and mRNA transport and biological process, this GO :0000166: nucleotide binding, this GO :0000166: nucleotide binding and also this GO :0003676: nucleic acid binding and also this GO :0003723: RNA binding and also this GO :0003730: mRNA 3'-UTR binding and also this GO :0005515: protein binding and also this GO :0044822: poly(A) RNA binding and also this GO :0045182: translation regulator activity and also this GO :0048027: mRNA 5'-UTR binding, this GO :0003676: nucleic acid binding, this GO :0003723: RNA binding, this GO :0003730: mRNA 3'-UTR binding, this GO :0005515: protein binding, this GO :0044822: poly(A) RNA binding, this GO :0045182: translation regulator activity, this GO :0048027: mRNA 5'-UTR binding, insulin-like growth factor 2 mRNA binding protein 3
Identity 28868
Gene IGF2BP3
Long gene name insulin like growth factor 2 mRNA binding protein 3
Synonyms gene name insulin-like growth factor 2 mRNA binding protein 3
Synonyms IMP-3 CT98 IMP3
Synonyms name IGF II mRNA binding protein 3 cancer/testis antigen 98
Locus 7p15, 3
Discovery year 2006-02-09
GenBank acession AF117108
Entrez gene record 10643
Pubmed identfication 9891060 9178771
RefSeq identity NM_006547
Classification RNA binding motif containing
Havana BLAST/BLAT OTTHUMG00000128445

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