Name : IGF2BP3 Antibody, ALEXA FLUOR 350
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN8740204934
| Long name | ALEXA FLUOR 350 Conjugated, IGF2BP3 Polyclonal Antibody |
| Also known as | Anti-IGF2BP3 PAb ALEXA FLUOR 350 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 350, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | IGF2BP3 |
| Specificity | This is a highly specific antibody against IGF2BP3 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 110-170/579 |
| Subcellular location | Nucleus, Cytoplasm |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Insulin-like growth factor 2 mRNA-binding protein 3 |
| Gene ID Number | 10643 |
| Swiss Prot | O00425 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Binds to beta-actin/ACTB and MYC transcripts, Binds to the 3'-UTR of CD44 mRNA and stabilizes it, Binds to the 5'-UTR of the insulin-like growth factor 2 (IGF2) mRNAs, It also modulates the rate and location at which target transcripts encounter the translational apparatus and shields them from endonuclease attacks or microRNA-mediated degradation, This transcript 'caging' into mRNPs allows mRNA transport and transient storage, hence promotes cell adhesion and invadopodia formation in cancer cells, RNA-binding factor that may recruits target transcripts to cytoplasmic protein-RNA complexes (mRNPs) |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 343nm/442nm |
| Synonyms | IMP-3 CT98 IMP3 |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | ALEXA FLUOR 350, Alexa Fluor |
| Gene target | IGF2BP3 |
| Short name | IGF2BP3 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 350 |
| Alternative name | ALEXA FLUOR 350, insulin-like growth factor 2 messenger RNA binding protein 3 (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | CT98 and IMP-3 and IMP3 and KOC and KOC1 and VICKZ3, IGF2BP3 and IDBG-630336 and ENSBTAG00000019406 and 539650, IGF2BP3 and IDBG-9675 and ENSG00000136231 and 10643, Igf2bp3 and IDBG-146190 and ENSMUSG00000029814 and 140488, mRNA 5'-UTR binding, nuclei, this GO :0000166 and nucleotide binding and molecular function this GO :0003676 and nucleic acid binding and molecular function this GO :0003723 and RNA binding and molecular function this GO :0003730 and mRNA 3'-UTR binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006412 and translation and biological process this GO :0009653 and anatomical structure morphogenesis and biological process this GO :0010467 and gene expression and biological process this GO :0017148 and negative regulation of translation and biological process this GO :0042035 and regulation of cytokine biosynthetic process and biological process this GO :0044822 and poly(A) RNA binding and molecular function this GO :0045182 and translation regulator activity and molecular function this GO :0048027 and mRNA 5'-UTR binding and molecular function this GO :0051028 and mRNA transport and biological process, this GO :0000166: nucleotide binding, this GO :0000166: nucleotide binding and also this GO :0003676: nucleic acid binding and also this GO :0003723: RNA binding and also this GO :0003730: mRNA 3'-UTR binding and also this GO :0005515: protein binding and also this GO :0044822: poly(A) RNA binding and also this GO :0045182: translation regulator activity and also this GO :0048027: mRNA 5'-UTR binding, this GO :0003676: nucleic acid binding, this GO :0003723: RNA binding, this GO :0003730: mRNA 3'-UTR binding, this GO :0005515: protein binding, this GO :0044822: poly(A) RNA binding, this GO :0045182: translation regulator activity, this GO :0048027: mRNA 5'-UTR binding, insulin-like growth factor 2 mRNA binding protein 3 |
| Identity | 28868 |
| Gene | IGF2BP3 |
| Long gene name | insulin like growth factor 2 mRNA binding protein 3 |
| Synonyms gene name | insulin-like growth factor 2 mRNA binding protein 3 |
| Synonyms name | IGF II mRNA binding protein 3 cancer/testis antigen 98 |
| Locus | 7p15, 3 |
| Discovery year | 2006-02-09 |
| GenBank acession | AF117108 |
| Entrez gene record | 10643 |
| Pubmed identfication | 9891060 9178771 |
| RefSeq identity | NM_006547 |
| Classification | RNA binding motif containing |
| Havana BLAST/BLAT | OTTHUMG00000128445 |