Name : IGF2BP3 Antibody, ALEXA FLUOR 647
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN9523008342
| Long name | ALEXA FLUOR 647 Conjugated, IGF2BP3 Polyclonal Antibody |
| Also known as | Anti-IGF2BP3 PAb ALEXA FLUOR 647 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 647, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | IGF2BP3 |
| Specificity | This is a highly specific antibody against IGF2BP3 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 110-170/579 |
| Subcellular location | Nucleus, Cytoplasm |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Insulin-like growth factor 2 mRNA-binding protein 3 |
| Gene ID Number | 10643 |
| Swiss Prot | O00425 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Binds to beta-actin/ACTB and MYC transcripts, Binds to the 3'-UTR of CD44 mRNA and stabilizes it, Binds to the 5'-UTR of the insulin-like growth factor 2 (IGF2) mRNAs, It also modulates the rate and location at which target transcripts encounter the translational apparatus and shields them from endonuclease attacks or microRNA-mediated degradation, This transcript 'caging' into mRNPs allows mRNA transport and transient storage, hence promotes cell adhesion and invadopodia formation in cancer cells, RNA-binding factor that may recruits target transcripts to cytoplasmic protein-RNA complexes (mRNPs) |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 650nm/665nm |
| Synonyms | IMP-3 CT98 IMP3 |
| Properties | ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the IGF2BP3 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | ALEXA FLUOR 647, Alexa Fluor |
| Gene target | IGF2BP3 |
| Short name | IGF2BP3 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 647 |
| Alternative name | ALEXA FLUOR 647, insulin-like growth factor 2 messenger RNA binding protein 3 (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | CT98 and IMP-3 and IMP3 and KOC and KOC1 and VICKZ3, IGF2BP3 and IDBG-630336 and ENSBTAG00000019406 and 539650, IGF2BP3 and IDBG-9675 and ENSG00000136231 and 10643, Igf2bp3 and IDBG-146190 and ENSMUSG00000029814 and 140488, mRNA 5'-UTR binding, nuclei, this GO :0000166 and nucleotide binding and molecular function this GO :0003676 and nucleic acid binding and molecular function this GO :0003723 and RNA binding and molecular function this GO :0003730 and mRNA 3'-UTR binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006412 and translation and biological process this GO :0009653 and anatomical structure morphogenesis and biological process this GO :0010467 and gene expression and biological process this GO :0017148 and negative regulation of translation and biological process this GO :0042035 and regulation of cytokine biosynthetic process and biological process this GO :0044822 and poly(A) RNA binding and molecular function this GO :0045182 and translation regulator activity and molecular function this GO :0048027 and mRNA 5'-UTR binding and molecular function this GO :0051028 and mRNA transport and biological process, this GO :0000166: nucleotide binding, this GO :0000166: nucleotide binding and also this GO :0003676: nucleic acid binding and also this GO :0003723: RNA binding and also this GO :0003730: mRNA 3'-UTR binding and also this GO :0005515: protein binding and also this GO :0044822: poly(A) RNA binding and also this GO :0045182: translation regulator activity and also this GO :0048027: mRNA 5'-UTR binding, this GO :0003676: nucleic acid binding, this GO :0003723: RNA binding, this GO :0003730: mRNA 3'-UTR binding, this GO :0005515: protein binding, this GO :0044822: poly(A) RNA binding, this GO :0045182: translation regulator activity, this GO :0048027: mRNA 5'-UTR binding, insulin-like growth factor 2 mRNA binding protein 3 |
| Identity | 28868 |
| Gene | IGF2BP3 |
| Long gene name | insulin like growth factor 2 mRNA binding protein 3 |
| Synonyms gene name | insulin-like growth factor 2 mRNA binding protein 3 |
| Synonyms name | IGF II mRNA binding protein 3 cancer/testis antigen 98 |
| Locus | 7p15, 3 |
| Discovery year | 2006-02-09 |
| GenBank acession | AF117108 |
| Entrez gene record | 10643 |
| Pubmed identfication | 9891060 9178771 |
| RefSeq identity | NM_006547 |
| Classification | RNA binding motif containing |
| Havana BLAST/BLAT | OTTHUMG00000128445 |