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IGFBP3 Antibody, FITC Conjugated

IGFBP3 Antibody, FITC Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, IGFBP3 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenIGFBP3
SpecificityThis is a highly specific antibody against IGFBP3
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range240-296/296
Subcellular locationSecreted
SourceKLH conjugated synthetic peptide derived from human IGFBP3
Gene ID number3486
Swiss ProtP17936
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Also exhibits IGF-independent antiproliferative and apoptotic effects mediated by its receptor TMEM219/IGFBP-3R, They alter the interaction of IGFs with their cell surface receptors, IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms IBP3 BP-53
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetIGFBP3 Conjugated
Short name FITC Conjugated, IGFBP3 Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, insulin-like growth factor binding protein 3 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target BP-53 and IBP3, IGFBP3 and IDBG-15809 and ENSG00000146674 and 3486, IGFBP3 and IDBG-633994 and ENSBTAG00000003994 and 282261, Igfbp3 and IDBG-148893 and ENSMUSG00000020427 and 16009, metal ion binding, nuclei, this GO :0001558 and regulation of cell growth and biological process this GO :0001649 and osteoblast differentiation and biological process this GO :0001933 and negative regulation of protein phosphorylation and biological process this GO :0001968 and fibronectin binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005520 and insulin-like growth factor binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005634 and nucleus and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0006915 and apoptotic process and biological process this GO :0008160 and protein tyrosine phosphatase activator activity and molecular function this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0009968 and negative regulation of signal transduction and biological process this GO :0010906 and regulation of glucose metabolic process and biological process this GO :0014912 and negative regulation of smooth muscle cell migration and biological process this GO :0016942 and insulin-like growth factor binding protein complex and cellular component this GO :0031994 and insulin-like growth factor I binding and molecular function this GO :0040008 and regulation of growth and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043085 and positive regulation of catalytic activity and biological process this GO :0043410 and positive regulation of MAPK cascade and biological process this GO :0043568 and positive regulation of insulin-like growth factor receptor signaling pathway and biological process this GO :0044267 and cellular protein metabolic process and biological process this GO :0044342 and type B pancreatic cell proliferation and biological process this GO :0045663 and positive regulation of myoblast differentiation and biological process this GO :0046872 and metal ion binding and molecular function this GO :0048662 and negative regulation of smooth muscle cell proliferation and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0001968: fibronectin binding, this GO :0001968: fibronectin binding and also this GO :0005515: protein binding and also this GO :0005520: insulin-like growth factor binding and also this GO :0008160: protein tyrosine phosphatase activator activity and also this GO :0031994: insulin-like growth factor I binding and also this GO :0046872: metal ion binding, this GO :0005515: protein binding, this GO :0005520: insulin-like growth factor binding, this GO :0008160: protein tyrosine phosphatase activator activity, this GO :0031994: insulin-like growth factor I binding, this GO :0046872: metal ion binding, insulin-like growth factor binding protein 3
Identity 5472
Gene IGFBP3
Long gene name insulin like growth factor binding protein 3
Synonyms gene name insulin-like growth factor binding protein 3
Synonyms name growth hormone-dependent binding protein acid stable subunit of the 140 K IGF complex binding protein 53 binding protein 29 IGF-binding protein 3
Locus 7p12, 3
Discovery year 1991-07-09
Entrez gene record 3486
Pubmed identfication 1695633
RefSeq identity NM_001013398
Classification Insulin like growth factor binding proteins
Havana BLAST/BLAT OTTHUMG00000023769
Locus Specific Databases LRG_68

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