Name : IGHD (607CT8.4.4) Monoclonal Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :211
SKU : GEN3918736731
| Long name | 4, 4) Monoclonal Antibody, IGHD (607CT8 |
| Also known as | 4, 4) Monoclonal Antibody, IGHD (607CT8 |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | IGHD |
| Specificity | This is a highly specific antibody against IGHD |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Monoclonal |
| Clone number | 4, 4, 607CT8 |
| Source | This IGHD antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 37-64 amino acids from the N-terminal region of human IGHD |
| Swiss Prot | P01880 |
| Tested Applications | WB |
| Recommended dilutions | WB(1:100~250) |
| Cross reactivity | Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | After the antigen binds to the B-cell receptor, IL10, IL1B, IgA, IgD also induces release of IL6, IgD is a potent inducer of TNF, IgM and IgD molecules present on B cells have identical V regions and antigen-binding sites, Monocytes seem to be the main producers of cytokines in vitro in the presence of IgD, Soluble IgD (sIgD) concentration in serum below those of IgG, The membrane-bound IgD (mIgD) induces the phosphorylation of CD79A and CD79B by the Src family of protein tyrosine kinases, and IL1RN, and IgM but much higher than that of IgE, and LIF from peripheral blood mononuclear cells, the secreted form sIgD is shut off, where it is coexpressed with IgM, IgD is the major antigen receptor isotype on the surface of most peripheral B-cells |
| Purification method | This antibody is prepared by Euglobin precipitation followed by dialysis against PBS, 09% (W/V) sodium azide, Purified monoclonal antibody supplied in PBS with 0 |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| About | Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Gene target | 4, 4) Monoclonal, IGHD (607CT8 |
| Short name | 4, 4) Monoclonal Antibody, IGHD (607CT8 |
| Technique | Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody |
| Alternative name | 4, 4) monoclonal (Antibody to), immunoglobulin heavy constant delta (607CT8 |
| Alternative technique | antibodies |
| Alternative to gene target | IGHD and IDBG-124395 and ENSG00000211898 and, multiple, protein binding, this GO :0005515 and protein binding and molecular function, this GO :0005515: protein binding, this GO :0005515: protein binding, immunoglobulin heavy constant delta |