| Long name | 1, 6) Monoclonal Antibody, IHH (363CT4 |
| Also known as | 1, 6) Monoclonal Antibody, IHH (363CT4 |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | IHH |
| Specificity | This is a highly specific antibody against IHH |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Monoclonal |
| Clone number | 1, 363CT4, 6 |
| Source | This IHH Monoclonal antibody is generated from mouses immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human IHH |
| Gene ID number | 3549 |
| Swiss Prot | Q14623 |
| Tested Applications | WB |
| Recommended dilutions | WB(1:1000-5000) |
| Cross reactivity | Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Binds to the patched (PTC) receptor, Implicated in endochondral ossification: may regulate the balance between growth and ossification of the developing bones, Induces the expression of parathyroid hormone-related protein (PTHRP) (By similarity), to activate the transcription of target genes, which functions in association with smoothened (SMO), Intercellular signal essential for a variety of patterning events during development |
| Purification method | 09% (W/V) sodium azide, Mouse monoclonal antibody supplied in crude ascites with 0 |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | HHG-2, HHG2, IHH, Indian hedgehog protein, BDA1 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| About | Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Gene target | 1, 6) Monoclonal, IHH (363CT4 |
| Short name | 1, 6) Monoclonal Antibody, IHH (363CT4 |
| Technique | Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody |
| Alternative name | 1, 6) monoclonal (Antibody to), Indian hedgehog (363CT4 |
| Alternative technique | antibodies |
| Alternative to gene target | BDA1 and HHG2, BT, Extracellular, IHH and IDBG-81274 and ENSG00000163501 and 3549, Ihh and IDBG-169082 and ENSMUSG00000006538 and 16147, peptidase activity, this GO :0001501 and skeletal system development and biological process this GO :0001503 and ossification and biological process this GO :0001569 and patterning of blood vessels and biological process this GO :0001649 and osteoblast differentiation and biological process this GO :0001701 and in utero embryonic development and biological process this GO :0001708 and cell fate specification and biological process this GO :0001763 and morphogenesis of a branching structure and biological process this GO :0001944 and vasculature development and biological process this GO :0001947 and heart looping and biological process this GO :0002053 and positive regulation of mesenchymal cell proliferation and biological process this GO :0003382 and epithelial cell morphogenesis and biological process this GO :0003406 and retinal pigment epithelium development and biological process this GO :0005113 and patched binding and molecular function this GO :0005509 and calcium ion binding and molecular function this GO :0005615 and extracellular space and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006029 and proteoglycan metabolic process and biological process this GO :0006508 and proteolysis and biological process this GO :0007154 and cell communication and biological process this GO :0007224 and smoothened signaling pathway and biological process this GO :0007267 and cell-cell signaling and biological process this GO :0007275 and multicellular organismal development and biological process this GO :0007389 and pattern specification process and biological process this GO :0008233 and peptidase activity and molecular function this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0009880 and embryonic pattern specification and biological process this GO :0009968 and negative regulation of signal transduction and biological process this GO :0016539 and intein-mediated protein splicing and biological process this GO :0030154 and cell differentiation and biological process this GO :0030704 and vitelline membrane formation and biological process this GO :0031012 and extracellular matrix and cellular component this GO :0031016 and pancreas development and biological process this GO :0032332 and positive regulation of chondrocyte differentiation and biological process this GO :0032355 and response to estradiol and biological process this GO :0032967 and positive regulation of collagen biosynthetic process and biological process this GO :0033085 and negative regulation of T cell differentiation in thymus and biological process this GO :0033088 and negative regulation of immature T cell proliferation in thymus and biological process this GO :0033089 and positive regulation of T cell differentiation in thymus and biological process this GO :0035264 and multicellular organism growth and biological process this GO :0035988 and chondrocyte proliferation and biological process this GO :0040008 and regulation of growth and biological process this GO :0043010 and camera-type eye development and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0045453 and bone resorption and biological process this GO :0045595 and regulation of cell differentiation and biological process this GO :0045596 and negative regulation of cell differentiation and biological process this GO :0045880 and positive regulation of smoothened signaling pathway and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046638 and positive regulation of alpha-beta T cell differentiation and biological process this GO :0046639 and negative regulation of alpha-beta T cell differentiation and biological process this GO :0048074 and negative regulation of eye pigmentation and biological process this GO :0048469 and cell maturation and biological process this GO :0048557 and embryonic digestive tract morphogenesis and biological process this GO :0048596 and embryonic camera-type eye morphogenesis and biological process this GO :0048666 and neuron development and biological process this GO :0048745 and smooth muscle tissue development and biological process this GO :0050679 and positive regulation of epithelial cell proliferation and biological process this GO :0051216 and cartilage development and biological process this GO :0060135 and maternal process involved in female pregnancy and biological process this GO :0060220 and camera-type eye photoreceptor cell fate commitment and biological process this GO :0060323 and head morphogenesis and biological process this GO :0061053 and somite development and biological process this GO :0072498 and embryonic skeletal joint development and biological process this GO :0090136 and epithelial cell-cell adhesion and biological process, this GO :0005113: patched binding, this GO :0005113: patched binding and also this GO :0005509: calcium ion binding and also this GO :0008233: peptidase activity, this GO :0005509: calcium ion binding, this GO :0008233: peptidase activity, 22104 and IDBG-643926 and ENSBTAG00000008452 and 522714, Indian hedgehog |
| Identity | 5956 |
| Gene | IHH |
| Long gene name | indian hedgehog |
| Synonyms gene name | Indian hedgehog (Drosophila) homolog Indian hedgehog homolog (Drosophila) |
| Synonyms | HHG2 BDA1 |
| Locus | 2q35 |
| Discovery year | 1995-03-21 |
| GenBank acession | L38517 |
| Entrez gene record | 3549 |
| Pubmed identfication | 7590746 14770182 |
| RefSeq identity | NM_002181 |
| Havana BLAST/BLAT | OTTHUMG00000154631 |
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