Name : IkB alpha Antibody
Supplier : NJS POLY
Price :199
SKU : GEN2107605803
| Category | Antibody |
| Concentration | 09% sodium azide, 4 with 0, In 1X PBS pH 7 |
| Form | Antigen affinity purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | IkB alpha |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications | ELISA, FACS, IF, IHC, WB |
| Recommended dilutions | Flow Cytometry: 1:10-1:50, IHC (Paraffin): 1:50-1:100, Immunofluorescence: 1:10-1:50, Western blot: 1:1000 |
| Notes | Titration of the IkB alpha antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use | This IkB alpha antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | P25963 |
| Purity | Antigen affinity |
| Description | Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime (where H is A, C, IKBKB) marks them for destruction via the ubiquitination pathway, Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA, R is an A or G purine, RELA, The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA or NFKBIB), and Y is a C or T pyrimidine), or RELB to form the NFKB complex, or T, thereby allowing activation of the NF-kappa-B complex, which inactivate NF-kappa-B by trapping it in the cytoplasm, NFKB1 or NFKB2 is bound to REL |
| Immunogen | A portion of amino acids 12-41 from the human protein was used as the immunogen for this IkB alpha antibody |
| Storage | Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the IkB alpha antibody and store frozen at -20 deg |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | IkB alpha |
| Short name | IkB alpha Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | IkB a (Antibody to) |
| Alternative technique | antibodies |