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IkB alpha Antibody

IkB alpha Antibody size: 0.08 ml 199

Supplier NJS POLY
Price 199
Size 0.08 ml
CategoryAntibody
Concentration09% sodium azide, 4 with 0, In 1X PBS pH 7
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenIkB alpha
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, FACS, IF, IHC, WB
Recommended dilutionsFlow Cytometry: 1:10-1:50, IHC (Paraffin): 1:50-1:100, Immunofluorescence: 1:10-1:50, Western blot: 1:1000
NotesTitration of the IkB alpha antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis IkB alpha antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P25963
PurityAntigen affinity
Description Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime (where H is A, C, IKBKB) marks them for destruction via the ubiquitination pathway, Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA, R is an A or G purine, RELA, The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA or NFKBIB), and Y is a C or T pyrimidine), or RELB to form the NFKB complex, or T, thereby allowing activation of the NF-kappa-B complex, which inactivate NF-kappa-B by trapping it in the cytoplasm, NFKB1 or NFKB2 is bound to REL
ImmunogenA portion of amino acids 12-41 from the human protein was used as the immunogen for this IkB alpha antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the IkB alpha antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetIkB alpha
Short nameIkB alpha Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameIkB a (Antibody to)
Alternative techniqueantibodies

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