Filters

IKBa Antibody

IKBa Antibody size: 0.4 ml 406

Supplier NJS POLY
Price 406
Size 0.4 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormPurified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenIKBa
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, WB
Recommended dilutionsWestern blot: 1:1000
NotesTitration of the IKBa antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis IKBa antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P25963
PurityPurified
Description Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime (where H is A, C, Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA, R is an A or G purine, RELA, The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA or NFKBIB), and Y is a C or T pyrimidine), or IKBKB) marks them for destruction via the ubiquitination pathway, or RELB to form the NFKB complex, or T, thereby allowing activation of the NF-kappa-B complex, which inactivate NF-kappa-B by trapping it in the cytoplasm, NFKB1 or NFKB2 is bound to REL
ImmunogenA portion of amino acids 1-30 from the human protein was used as the immunogen for this IKBa antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the IKBa antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetIKBa
Short nameIKBa Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameIKBa (Antibody to)
Alternative techniqueantibodies
Identity 7797
Gene NFKBIA
Long gene name NFKB inhibitor alpha
Synonyms gene NFKBI
Synonyms gene name alpha , nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor
Synonyms IKBA MAD-3 IkappaBalpha
Synonyms name NF-kappa-B inhibitor alpha
Locus 14q13, 2
Discovery year 1992-02-13
Entrez gene record 4792
Pubmed identfication 1829648
RefSeq identity NM_020529
Classification Ankyrin repeat domain containing
Havana BLAST/BLAT OTTHUMG00000140220
Locus Specific Databases NFKBIAbase: Mutation registry for Autosomal dominant anhidrotic ectodermal dysplasia and T-cell immunodeficiency LRG_89

Similar products

Subscribe to our Newsletter