Name : IKK beta(Ser471) Antibody, Cy3 Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :368
SKU : GEN7531938214
| Long name | Cy3 Conjugated, IKK beta(Ser471) Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | cy3 conjugation kit |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | IKK beta Ser471 |
| Specificity | This is a highly specific antibody against IKK beta Ser471 |
| Modification | Phosphorylation |
| Modification site | Ser471 |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic phosphopeptide derived from human IKK beta around the phosphorylation site of Ser471 |
| Gene ID number | 3551 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Additionally, IKK beta, IKK beta activity can also be regulated by MEKK1, IKK beta autophosphorylates which in turn decreases IKK activity and prevents prolonged activation of the inflammatory response, IKK beta has been shown to activate NF-kB and phosphorylate IKB alpha and beta, IKK gamma and IKAP, Once activated, Phosphorylation of 2 sites at the activation loop of IKK beta is essential for activation of IKK by TNF and IL1, Phosphorylation of I-Kappa-B on a serine residue by the IKK complex frees NF-kB from I-Kappa-B and marks it for degradation via ubiquination, IKK beta (I-Kappa-B kinase-beta) is a member of the IKK complex which is composed of IKK alpha |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 512, 550nm/570, 615nm |
| Synonyms | I kappa B kinase beta, IKBKB, IKK Î, IKK 2, IKK B, IKK beta, IKK beta phospho Ser471, IKKÎ, IKK2, IKKB, IKKB_HUMAN, IKKI kappa B kinase 2, IkBKB, Inhibitor of kappa light chain gene enhancer in B cells, Inhibitor of kappa light polypeptide gene enhancer in B cells, Inhibitor of kappa light polypeptide gene enhancer in B cells kinase beta, Inhibitor of nuclear factor kappa B kinase beta subunit, Inhibitor of nuclear factor kappa B kinase subunit beta, MGC131801, NFKBIKB, Nuclear factor NF kappa B inhibitor kinase beta, Nuclear factor of kappa light chain gene enhancer in B cells inhibitor, p-IKK beta Ser471, ², ², IKK beta phospho S471 |
| Properties | 1 of the IKK beta(Ser471) Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | IKK beta(Ser471) Conjugated |
| Short name | Conjugated, IKK beta(Ser471) Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Cy3 |
| Alternative name | cyanine 3 coupled, IKK b(Ser471) (Antibody to) |
| Alternative technique | antibodies |