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IKK beta(Ser740) Antibody, FITC Conjugated

IKK beta(Ser740) Antibody, FITC Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, IKK beta(Ser740) Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenIKK beta Ser740
SpecificityThis is a highly specific antibody against IKK beta Ser740
ModificationPhosphorylation
Modification siteSer740
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human IKK beta around the phosphorylation site of Ser740
Gene ID number3551
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Additionally, IKK beta, IKK beta activity can also be regulated by MEKK1, IKK beta autophosphorylates which in turn decreases IKK activity and prevents prolonged activation of the inflammatory response, IKK beta has been shown to activate NF-kB and phosphorylate IKB alpha and beta, IKK gamma and IKAP, Once activated, Phosphorylation of 2 sites at the activation loop of IKK beta is essential for activation of IKK by TNF and IL1, Phosphorylation of I-Kappa-B on a serine residue by the IKK complex frees NF-kB from I-Kappa-B and marks it for degradation via ubiquination, IKK beta (I-Kappa-B kinase-beta) is a member of the IKK complex which is composed of IKK alpha
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms I kappa B kinase beta, IKK Î, IKK 2, IKK B, IKK beta, IKK beta phospho Ser740, IKKÎ, IKK2, IKKB, IKKB_HUMAN, IKKI kappa B kinase 2, IkBKB, Inhibitor of kappa light chain gene enhancer in B cells, Inhibitor of kappa light polypeptide gene enhancer in B cells, Inhibitor of kappa light polypeptide gene enhancer in B cells kinase beta, Inhibitor of nuclear factor kappa B kinase beta subunit, Inhibitor of nuclear factor kappa B kinase subunit beta, MGC131801, NFKBIKB, Nuclear factor NF kappa B inhibitor kinase beta, Nuclear factor of kappa light chain gene enhancer in B cells inhibitor, p-IKK beta Ser740, ², ², IKK beta phospho S740
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetIKK beta(Ser740) Conjugated
Short name FITC Conjugated, IKK beta(Ser740) Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, IKK b(Ser740) (Antibody to)
Alternative techniqueantibodies

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