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IKK beta(Tyr188) Antibody

IKK beta(Tyr188) Antibody size: 0.1ml 281

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 281
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameIKK beta(Tyr188) Primary Polyclonal Antibody
Also known asIKK beta(Tyr188) PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenIKK beta Tyr188
SpecificityThis is a highly specific antibody against IKK beta Tyr188
Modification(s)Phosphorylation
Modification site(s)Tyr188
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human IKK beta around the phosphorylation site of Tyr188
Gene ID number3551
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Additionally, IKK beta, IKK beta activity can also be regulated by MEKK1, IKK beta autophosphorylates which in turn decreases IKK activity and prevents prolonged activation of the inflammatory response, IKK beta has been shown to activate NF-kB and phosphorylate IKB alpha and beta, IKK gamma and IKAP, Once activated, Phosphorylation of 2 sites at the activation loop of IKK beta is essential for activation of IKK by TNF and IL1, Phosphorylation of I-Kappa-B on a serine residue by the IKK complex frees NF-kB from I-Kappa-B and marks it for degradation via ubiquination, IKK beta (I-Kappa-B kinase-beta) is a member of the IKK complex which is composed of IKK alpha
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names I kappa B kinase beta, IKK Î, IKK 2, IKK B, IKK beta, IKK beta phospho Tyr188, IKKÎ, IKK2, IKKB, IKKB_HUMAN, IKKI kappa B kinase 2, IkBKB, Inhibitor of kappa light chain gene enhancer in B cells, Inhibitor of kappa light polypeptide gene enhancer in B cells, Inhibitor of kappa light polypeptide gene enhancer in B cells kinase beta, Inhibitor of nuclear factor kappa B kinase beta subunit, Inhibitor of nuclear factor kappa B kinase subunit beta, MGC131801, NFKBIKB, Nuclear factor NF kappa B inhibitor kinase beta, Nuclear factor of kappa light chain gene enhancer in B cells inhibitor, p-IKK beta Tyr188, ², ², IKK beta phospho Y188
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetIKK beta(Tyr188)
Short nameIKK beta(Tyr188) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameIKK b(Tyr188) (Antibody to)
Alternative techniqueantibodies

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