Name : IKK beta(Tyr188) Antibody, ALEXA FLUOR 594
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :350
SKU : GEN8953559907
| Long name | ALEXA FLUOR 594 Conjugated, IKK beta(Tyr188) Polyclonal Antibody |
| Also known as | Anti-IKK beta Tyr188 PAb ALEXA FLUOR 594 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 594, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | IKK beta Tyr188 |
| Specificity | This is a highly specific antibody against IKK beta Tyr188 |
| Modification | Phosphorylation |
| Modification Site | Tyr188 |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic phosphopeptide derived from human IKK beta around the phosphorylation site of Tyr188 |
| Gene ID Number | 3551 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Additionally, IKK beta, IKK beta activity can also be regulated by MEKK1, IKK beta autophosphorylates which in turn decreases IKK activity and prevents prolonged activation of the inflammatory response, IKK beta has been shown to activate NF-kB and phosphorylate IKB alpha and beta, IKK gamma and IKAP, Once activated, Phosphorylation of 2 sites at the activation loop of IKK beta is essential for activation of IKK by TNF and IL1, Phosphorylation of I-Kappa-B on a serine residue by the IKK complex frees NF-kB from I-Kappa-B and marks it for degradation via ubiquination, IKK beta (I-Kappa-B kinase-beta) is a member of the IKK complex which is composed of IKK alpha |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | I kappa B kinase beta, IKK Î, IKK 2, IKK B, IKK beta, IKK beta phospho Tyr188, IKKÎ, IKK2, IKKB, IKKB_HUMAN, IKKI kappa B kinase 2, IkBKB, Inhibitor of kappa light chain gene enhancer in B cells, Inhibitor of kappa light polypeptide gene enhancer in B cells, Inhibitor of kappa light polypeptide gene enhancer in B cells kinase beta, Inhibitor of nuclear factor kappa B kinase beta subunit, Inhibitor of nuclear factor kappa B kinase subunit beta, MGC131801, NFKBIKB, Nuclear factor NF kappa B inhibitor kinase beta, Nuclear factor of kappa light chain gene enhancer in B cells inhibitor, p-IKK beta Tyr188, ², ², IKK beta phospho Y188 |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | 594, ALEXA FLUOR®, Alexa Fluor |
| Conjugated | Alexa conjugate 1 |
| Gene target | IKK beta(Tyr188) |
| Short name | IKK beta(Tyr188) Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 594 |
| Alternative name | ALEXA FLUOR 594, IKK b(Tyr188) (Antibody to) |
| Alternative technique | antibodies |