Name : IKK gamma Antibody / NEMO
Supplier : NJS POLY
Price :406
SKU : GEN6684510809
| Category | Antibody |
| Concentration | 2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form | Antigen affinity purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | IKK gamma / NEMO |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications | WB |
| Recommended dilutions | 5-1ug/ml, Western blot: 0 |
| Notes | Optimal dilution of the IKKG antibody should be determined by the researcher |
| Added buffer | 025% sodium azide, 5% BSA and 0, Lyophilized from 1X Phosphate Buffered Saline (PBS) with 2 |
| Intented use | This antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | Q9Y6K9 |
| Purity | Antigen affinity |
| Description | A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome, Mutations in this gene result in incontinentia pigmenti, This gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex, also known as inhibitor of nuclear factor kappa-B kinase subunit gamma (IKK<, and other pathways, and several other types of immunodeficiencies, cell survival, hypohidrotic ectodermal dysplasia, immunity, is a protein that in humans is encoded by the IKBKG gene, which activates NF-kappaB resulting in activation of genes involved in inflammation, ), /font>, NF-kappa-B essential modulator (NEMO), font face=symbol>, g< |
| Immunogen | Amino acids 207-246 (QSVEAALRMERQAASEEKRKLAQLQVAYHQLFQEYDNHIK-human) were used as the immunogen for the IKKG antibody |
| Storage | Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the IKKG antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | IKK gamma / NEMO |
| Short name | IKK gamma Antibody / NEMO |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | IKK g (Antibody to) / NEMO |
| Alternative technique | antibodies |
| Identity | 5961 |
| Gene | IKBKG |
| Long gene name | inhibitor of nuclear factor kappa B kinase subunit gamma |
| Synonyms gene | IP2 IP1 |
| Synonyms gene name | incontinentia pigmenti inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma |
| Synonyms | IKK-gamma NEMO Fip3p FIP-3 FIP3 ZC2HC9 |
| Locus | Xq28 |
| Discovery year | 1998-09-30 |
| GenBank acession | AF074382 |
| Entrez gene record | 8517 |
| Pubmed identfication | 9751060 10087442 11590134 |
| RefSeq identity | NM_003639 |
| Classification | Zinc fingers C2HC-type |
| Havana BLAST/BLAT | OTTHUMG00000024234 |
| Locus Specific Databases | IKBKGbase: Mutation registry for Nemo deficiency Mental Retardation database LRG_70 |