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IKK gamma (Ser376) Antibody

IKK gamma (Ser376) Antibody size: 0.1ml 281

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 281
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameIKK gamma (Ser376) Primary Polyclonal Antibody
Also known asIKK gamma (Ser376) PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenIKK gamma Ser376
SpecificityThis is a highly specific antibody against IKK gamma Ser376
Modification(s)Phosphorylation
Modification site(s)Ser376
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range360-390/419
Subcellular location Nucleus, Cytoplasm
SourceKLH conjugated synthetic phosphopeptide derived from human IKBKG around the phosphorylation site of Ser376
Gene ID number8517
Swiss ProtQ9Y6K9
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivityHuman
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Also considered to be a mediator for TAX activation of NF-kappa-B, Could be implicated in NF-kappa-B-mediated protection from cytokine toxicity, Essential for viral activation of IRF3, However, Involved in TLR3- and IFIH1-mediated antiviral innate response, Its binding to scaffolding polyubiquitin seems to play a role in IKK activation by multiple signaling receptor pathways, the specific type of polyubiquitin recognized upon cell stimulation (either 'Lys-63'-linked or linear polyubiquitin) and its functional importance is reported conflictingly, this function requires 'Lys-27'-linked polyubiquitination, Regulatory subunit of the IKK core complex which phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names AMCBX1, FIP-3, FIP3, Fip3p, I-kappa-B kinase subunit gamma, IKBKG, IKK-gamma, IKKAP1, IKKG, IMD33, IP1, IP2, IPD2, IkB kinase subunit gamma, IkB kinase-associated protein 1, Inhibitor of nuclear factor kappa-B kinase subunit gamma, NEMO, NF-kappa-B essential modifier, NF-kappa-B essential modulator, ZC2HC9, IP
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetIKK gamma (Ser376)
Short nameIKK gamma (Ser376) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameIKK g (Ser376) (Antibody to)
Alternative techniqueantibodies

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