Filters

IL-2R gamma Antibody

IL-2R gamma Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameIL-2R gamma Primary Polyclonal Antibody
Also known asIL-2R gamma PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenIL-2R gamma
SpecificityThis is a highly specific antibody against IL-2R gamma
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range135-185/369
Subcellular locationExtracellular
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human IL-2R gamma
Gene ID number3561
Swiss ProtP31785
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Acting through the IL2R gamma containing complexes, B cells, CD122 (IL2R beta), CD124 (IL4R alpha), CD127 (IL7R), Chemical cross linking experiments reveal that IL2R gamma is able to bind cytokines only when complexed with these other cell surface proteins, Cytokine binding to the IL2R gamma containing receptor complexes activates these tyrosine kinases, IL2, IL2 and IL15 exert their effects through cascades, IL2R gamma associates with several cytoplasmic tyrosine kinases including JAK3 (Janus Kinase 3), IL2R gamma complexed with other cell surface proteins forms receptors for the cytokines IL2, IL2R gamma forms complexes with other cell surface proteins including CD25 (IL2R alpha), IL2R gamma is also known as CD132, IL4, IL7, IL7, IL7 exerts its effects through a cascade that results in VDJ immunoglobulin gene rearrangement, IL9, In addition to interacting with other cell surface glycoproteins, JAK1, NK cells, Once activated, STAT5, Syc, The activated tyrosine kinases also phosphorylate downstream regulators including STAT3 (Signal Transducer and Activator of Transcription 3), The various cytokines that bind to IL2R gamma containing receptor complexes exert their effects through unique repertoires of cytoplasmic signaling molecules, and IL15, and IL9 exert their effects through cascades, and Lyc, and STAT6, and gamma c, and neutrophils, and others, common cytokine receptor gamma chain, creating docking sites for signaling molecules such as PI 3 kinase, macrophages, monocytes, these cytokines regulate lymphocyte development and activation, these tyrosine kinases phosphorylate their associated receptors, which activate STAT3 and STAT5, which activate the MAP kinase cascade, while IL4 activates STAT6, Interleukin 2 (IL2) receptor gamma chain (IL5212R gamma) is a cell surface glycoprotein expressed by a variety of leukocytes including T cells
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names CD132, CIDX, Cytokine receptor common subunit gamma, IL-2 receptor subunit gamma, IL-2R subunit gamma, IL-2RG, IL2RG, IMD4, Interleukin-2 receptor subunit gamma, SCIDX, SCIDX1, gammaC, P64
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetIL-2R gamma
Short nameIL-2R gamma Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameInterleukin-2R g (Antibody to)
Alternative techniqueantibodies

Similar products

Subscribe to our Newsletter